Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SP670_RS09375 Genome accession   NC_014498
Coordinates   1756116..1756775 (+) Length   219 a.a.
NCBI ID   WP_000565019.1    Uniprot ID   A0A0T9ICH6
Organism   Streptococcus pneumoniae 670-6B     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1751116..1761775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP670_RS09335 (SP670_1877) mgaSpn 1751272..1752753 (-) 1482 WP_001205278.1 virulence factor transcriptional regulator MgaSpn -
  SP670_RS09340 (SP670_1878) - 1753196..1753360 (+) 165 WP_001809002.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  SP670_RS09345 (SP670_1879) amaP 1753444..1754010 (+) 567 WP_000030213.1 alkaline shock response membrane anchor protein AmaP -
  SP670_RS09350 (SP670_1880) - 1754022..1754192 (+) 171 WP_000455066.1 DUF2273 domain-containing protein -
  SP670_RS09355 (SP670_1881) - 1754231..1754839 (+) 609 WP_000064115.1 Asp23/Gls24 family envelope stress response protein -
  SP670_RS09360 (SP670_1882) - 1754870..1755073 (+) 204 WP_000109957.1 CsbD family protein -
  SP670_RS09365 - 1755183..1755476 (-) 294 WP_306293410.1 transposase -
  SP670_RS09370 (SP670_1883) - 1755600..1756046 (-) 447 WP_000155404.1 GNAT family N-acetyltransferase -
  SP670_RS09375 (SP670_1884) cclA/cilC 1756116..1756775 (+) 660 WP_000565019.1 A24 family peptidase Machinery gene
  SP670_RS09380 (SP670_1885) - 1756827..1757978 (-) 1152 WP_000481754.1 XRE family transcriptional regulator -
  SP670_RS09385 (SP670_1886) - 1757993..1758724 (-) 732 WP_000934018.1 hypothetical protein -
  SP670_RS13105 - 1758950..1759054 (+) 105 Protein_1795 prepilin peptidase -
  SP670_RS09390 (SP670_1887) trpA 1759026..1759802 (-) 777 WP_001127046.1 tryptophan synthase subunit alpha -
  SP670_RS09395 (SP670_1888) trpB 1759795..1761018 (-) 1224 WP_000331257.1 tryptophan synthase subunit beta -
  SP670_RS09400 (SP670_1889) - 1760996..1761595 (-) 600 WP_000169927.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24879.99 Da        Isoelectric Point: 7.6418

>NTDB_id=38306 SP670_RS09375 WP_000565019.1 1756116..1756775(+) (cclA/cilC) [Streptococcus pneumoniae 670-6B]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=38306 SP670_RS09375 WP_000565019.1 1756116..1756775(+) (cclA/cilC) [Streptococcus pneumoniae 670-6B]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTAGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATTCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T9ICH6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae Rx1

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae D39

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae R6

96.347

100

0.963
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

86.301

100

0.863

Multiple sequence alignment