Detailed information NTG0381009

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: HB370_RS14680
• Genome accession: NZ_CP050504
• Coordinates: 3266268..3267554 (-)
• Length: 428 a.a.
• NCBI ID: WP_014672712.1
• Uniprot ID: A0A101QM25
• Organism: Streptomyces sp. DSM 40868
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 3261268..3272554

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HB370_RS14670 (HB370_14670)	-	3262449..3265073 (-)	2625	WP_030790416.1	valine--tRNA ligase	-
HB370_RS14675 (HB370_14675)	-	3265211..3266194 (+)	984	WP_030790414.1	membrane protein	-
HB370_RS14680 (HB370_14680)	clpX	3266268..3267554 (-)	1287	WP_014672712.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
HB370_RS14685 (HB370_14685)	clpP	3267725..3268390 (-)	666	WP_030608200.1	ATP-dependent Clp protease proteolytic subunit	Regulator
HB370_RS14690 (HB370_14690)	clpP	3268458..3269063 (-)	606	WP_030790409.1	ATP-dependent Clp protease proteolytic subunit	Regulator
HB370_RS14695 (HB370_14695)	tig	3269405..3270775 (-)	1371	WP_030790407.1	trigger factor	-
HB370_RS14710 (HB370_14710)	-	3271842..3272036 (-)	195	WP_030790404.1	hypothetical protein	-

Sequence

Protein

• Length: 428 a.a.
• Molecular weight: 46626.50 Da
• Isoelectric Point: 4.7331

>NTDB_id=381009 HB370_RS14680 WP_014672712.1 3266268..3267554(-) (clpX) [Streptomyces sp. DSM 40868]
MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLEGYVVGQEA
AKKALSVAVYNHYKRVQAGENGGASGRDDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGED
VENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQ
IDTTNVLFIVGGAFAGLEKIIEARAGAKGIGFGATILSKRELEAKDVFEDVMPEDLVKFGMIPEFIGRLPVITSVHNLDR
EALLKILVEPRNALVKQYQRLFELDGVELDFEREALEAIADQAILRQTGARGLRAIMEEVLQGVMYEVPSRKDVARVVIT
ADVVLSNVNPTLIPRDARGRGSGEQKTA

Nucleotide

• Length: 1287 bp

>NTDB_id=381009 HB370_RS14680 WP_014672712.1 3266268..3267554(-) (clpX) [Streptomyces sp. DSM 40868]
GTGGCACGCATCGGTGACGGCGGCGATCTGCTCAAGTGCTCGTTCTGCGGCAAGAGCCAGAAGCAGGTCAAGAAGCTCAT
CGCAGGGCCCGGTGTGTACATCTGCGACGAGTGCATCGATCTCTGTAACGAGATCATCGAGGAAGAGCTCGCGGAGACCA
GCGAGGTGCGCTGGGAGGAGCTGCCCAAGCCGCGCGAGATCTACGAGTTCCTCGAGGGCTACGTGGTCGGCCAGGAGGCC
GCCAAGAAGGCTCTGTCGGTCGCGGTGTACAACCACTACAAGCGGGTCCAGGCGGGCGAGAACGGCGGCGCGAGCGGCCG
GGACGACGCGATCGAACTGGCGAAGTCCAACATCCTGCTGCTCGGTCCCACCGGCTCCGGCAAGACCCTGCTGGCGCAGA
CCCTGGCGCGCATGCTGAACGTCCCGTTCGCGATCGCCGACGCCACGGCGCTGACCGAGGCGGGCTATGTCGGCGAGGAC
GTCGAGAACATCCTGCTGAAGCTGATCCAGGCGGCGGACTACGACGTCAAGAAGGCCGAGACCGGGATCATCTACATCGA
CGAGATCGACAAGGTCGCCCGCAAGAGCGAGAACCCGTCGATCACCCGGGACGTGAGCGGCGAGGGCGTCCAGCAGGCGC
TGCTGAAGATCCTGGAGGGCACGACGGCCTCGGTCCCGCCGCAGGGCGGCCGCAAGCACCCGCACCAGGAGTTCATCCAG
ATCGACACGACGAACGTGCTGTTCATCGTGGGCGGTGCCTTCGCGGGCCTGGAGAAGATCATCGAGGCCCGGGCCGGCGC
CAAGGGCATCGGCTTCGGCGCGACGATCCTGTCCAAGCGCGAGCTGGAGGCCAAGGACGTCTTCGAGGACGTCATGCCGG
AGGACCTGGTCAAGTTCGGCATGATCCCCGAGTTCATCGGCCGGCTGCCCGTGATCACGTCCGTGCACAACCTGGATCGC
GAGGCGCTGCTGAAGATCCTGGTCGAGCCGCGCAACGCCCTGGTCAAGCAGTACCAGCGCCTGTTCGAACTCGACGGCGT
GGAGCTGGACTTCGAGCGCGAGGCGCTGGAGGCCATCGCCGACCAGGCCATCCTCCGCCAGACCGGTGCCCGTGGCCTGC
GCGCCATCATGGAGGAGGTCCTCCAGGGCGTGATGTACGAGGTGCCGTCCCGCAAGGACGTGGCCCGCGTGGTCATCACC
GCCGACGTGGTCCTCTCCAACGTCAACCCCACCCTGATCCCGCGCGACGCCCGCGGCCGGGGTTCGGGGGAGCAGAAGAC
GGCGTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (115-312)

• ClpX C4-type zinc finger (zf-C4_ClpX) (11-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (318-395)

3D structure

• AlphaFold DB: A0A101QM25

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	63.184	93.925	0.593
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.745	96.028	0.526