Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   FXN57_RS02870 Genome accession   NZ_CP043005
Coordinates   541846..543201 (-) Length   451 a.a.
NCBI ID   WP_148363148.1    Uniprot ID   -
Organism   Aggregatibacter actinomycetemcomitans strain PN_696     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 536846..548201
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FXN57_RS02845 (FXN57_02840) - 537609..537995 (+) 387 WP_392388731.1 Mov34/MPN/PAD-1 family protein -
  FXN57_RS02850 (FXN57_02845) - 537988..538818 (+) 831 WP_148323777.1 DUF6602 domain-containing protein -
  FXN57_RS02855 (FXN57_02850) - 539083..539937 (-) 855 WP_148323779.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  FXN57_RS02860 (FXN57_02855) aroB 539940..541028 (-) 1089 WP_148323781.1 3-dehydroquinate synthase -
  FXN57_RS02865 (FXN57_02860) aroK 541052..541579 (-) 528 WP_005555432.1 shikimate kinase AroK -
  FXN57_RS02870 (FXN57_02865) comE 541846..543201 (-) 1356 WP_148363148.1 type IV pilus secretin PilQ Machinery gene
  FXN57_RS02875 (FXN57_02870) - 543222..543614 (-) 393 WP_148363149.1 competence protein ComD -
  FXN57_RS02880 (FXN57_02875) - 543614..544138 (-) 525 WP_148323789.1 type II secretion system protein M -
  FXN57_RS02885 (FXN57_02880) - 544135..544653 (-) 519 WP_148323791.1 PilN domain-containing protein -
  FXN57_RS02890 (FXN57_02885) - 544664..545473 (-) 810 WP_148327217.1 competence protein ComA -
  FXN57_RS02895 (FXN57_02890) - 545607..548174 (+) 2568 WP_005581959.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 451 a.a.        Molecular weight: 49347.53 Da        Isoelectric Point: 6.5120

>NTDB_id=380163 FXN57_RS02870 WP_148363148.1 541846..543201(-) (comE) [Aggregatibacter actinomycetemcomitans strain PN_696]
MKSILSRQLKCGLLFGCFLSLAVQAEQNPVFSIRLKQAPLVPTLQQLALAHNTNLIIDDELQGTVSLQLENVDLDQLFRS
VAKIKQLDLWQENGIYYFTKGDTNTKFAGKMEEPFPLSVSMAEEPAQLTTATIKLHFAKASEVMKSLTGGSGSLLSPNGS
ITFDDRSNLLLIQDEPRSVHNIKKLIKELDKPIEQIAIEARIVTINDESLKELGGRWGIFSPTDNAHRVGGSLAGNGFDN
LVNQLNVNFPTTTTPAGSVALQVVKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTELPYILVNEKSGSQ
SVEFREAVLGLEVTPHISQDKQILLDLIVSQNSPGSRVAYGLGEVVSIDKQEINTQVFAKDGETIVLGGVFSDTITKGTD
KVPVLGDIPGIKHLFSKESERHQKRELVIFVTPHILRKGAPRTLSNKSESG

Nucleotide


Download         Length: 1356 bp        

>NTDB_id=380163 FXN57_RS02870 WP_148363148.1 541846..543201(-) (comE) [Aggregatibacter actinomycetemcomitans strain PN_696]
ATGAAATCGATTCTTTCCCGACAGCTAAAGTGCGGTCTGCTTTTCGGGTGTTTTTTAAGTCTTGCGGTGCAGGCGGAACA
AAATCCGGTGTTTTCCATTCGGCTGAAACAGGCACCACTGGTTCCGACTTTGCAGCAGTTGGCATTAGCCCACAATACCA
ATTTGATTATTGACGACGAGCTGCAGGGCACGGTGTCGTTACAGTTGGAAAACGTGGATTTGGATCAGCTGTTTCGTTCT
GTGGCGAAAATTAAACAACTGGATTTATGGCAGGAAAACGGCATTTATTATTTCACTAAAGGCGACACCAACACGAAATT
TGCCGGCAAAATGGAAGAGCCTTTCCCTCTTTCAGTGTCCATGGCGGAAGAACCGGCACAGCTGACCACGGCGACCATTA
AATTACACTTTGCCAAAGCGTCGGAAGTGATGAAATCCCTCACCGGGGGGAGCGGTTCCCTGTTGTCGCCTAACGGCAGT
ATCACTTTCGACGATCGTAGCAATTTGTTGCTGATTCAGGATGAACCGCGTTCCGTCCACAACATAAAAAAGCTGATTAA
GGAACTTGATAAACCCATTGAGCAAATCGCCATTGAAGCGCGCATTGTCACCATTAACGATGAAAGCCTGAAAGAACTGG
GCGGGCGCTGGGGGATCTTCAGCCCGACGGACAACGCCCATCGCGTCGGCGGCAGTTTGGCGGGCAACGGCTTTGATAAT
CTTGTCAATCAGTTAAACGTAAATTTTCCCACGACCACGACACCGGCAGGCTCTGTGGCGTTACAGGTTGTGAAAATCAA
TGGGCGACTTTTAGACTTAGAATTGACCGCACTTGAACGGGAAAATAATGTGGAAATCATCGCAAGCCCACGACTGCTAA
CGACAAACAAAAAAAGCGCCAGCATCAAACAGGGGACGGAATTGCCCTATATTCTGGTGAACGAAAAAAGCGGTTCGCAA
AGCGTAGAATTTCGTGAGGCGGTACTAGGTTTGGAAGTCACACCGCACATTTCGCAGGATAAACAAATTCTGTTAGATCT
TATCGTCAGCCAAAACTCGCCGGGCAGCCGTGTGGCATACGGTTTGGGCGAAGTGGTTTCTATTGATAAACAGGAGATTA
ATACACAAGTCTTCGCCAAGGACGGCGAAACCATTGTGCTGGGCGGTGTATTTAGCGATACCATCACCAAAGGCACCGAT
AAAGTGCCGGTGCTGGGTGACATTCCGGGTATTAAACATTTATTCAGCAAGGAAAGTGAACGCCATCAAAAACGCGAGCT
GGTGATTTTTGTCACACCACATATTTTGCGTAAAGGCGCCCCCCGGACGCTTTCAAACAAAAGCGAATCGGGGTAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(130-195)

Bacterial type II and III secretion system protein (Secretin)

(277-437)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

70.852

98.891

0.701
  comE Haemophilus influenzae 86-028NP

70.805

96.452

0.683
  comE Glaesserella parasuis strain SC1401

52

94.235

0.49
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.589

94.9

0.395
  pilQ Vibrio cholerae strain A1552

41.589

94.9

0.395
  pilQ Vibrio campbellii strain DS40M4

41.014

96.231

0.395

Multiple sequence alignment