Detailed information NTG0379858

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: FWK48_RS03520
• Genome accession: NZ_CP042987
• Coordinates: 764390..765523 (-)
• Length: 377 a.a.
• NCBI ID: WP_132994602.1
• Uniprot ID: A0AAX2S358
• Organism: Histophilus somni strain UOC-KLM-ATR-08
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 759390..770523

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FWK48_RS03500 (FWK48_03500)	galU	760768..761655 (+)	888	WP_012340251.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
FWK48_RS03505 (FWK48_03505)	-	761703..762566 (-)	864	WP_132994600.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
FWK48_RS03510 (FWK48_03510)	aroB	762573..763661 (-)	1089	WP_136121399.1	3-dehydroquinate synthase	-
FWK48_RS03515 (FWK48_03515)	aroK	763681..764208 (-)	528	WP_012340254.1	shikimate kinase AroK	-
FWK48_RS03520 (FWK48_03520)	comE	764390..765523 (-)	1134	WP_132994602.1	type IV pilus secretin PilQ	Machinery gene
FWK48_RS03525 (FWK48_03525)	-	765539..766036 (-)	498	WP_132994603.1	competence protein	-
FWK48_RS03530 (FWK48_03530)	-	766040..766579 (-)	540	WP_132994604.1	PilN domain-containing protein	-
FWK48_RS03535 (FWK48_03535)	-	766583..767368 (-)	786	WP_132994605.1	competence protein ComA	-
FWK48_RS03540 (FWK48_03540)	-	767493..770033 (+)	2541	WP_132994606.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 42389.42 Da
• Isoelectric Point: 6.4079

>NTDB_id=379858 FWK48_RS03520 WP_132994602.1 764390..765523(-) (comE) [Histophilus somni strain UOC-KLM-ATR-08]
MLIKNFLYFFLFLFTVSVELSARDPFDKRQRSIKKETNIQLDTKENLSKSTNEPNLTTTSIKLHYAKAADVMKSLTTGQG
SWLSSNGTFSFDERSNLLLIQDNQETLNALKKLIKEMDQPIEQIAIEARIVTISDENLKELGVRWGIFEPTNNAHHLSGN
LAANGFQHLTEQLNVNFATTATPAGSIALQIAKINDRLLDLELTALERENNVEIIASPRLLTTNKQSASIKQGTEIPYVI
TGKKSDEQKVEFREAVLGLEVTPHISKDNTILLDLLVSQNSPGSRITYGQNEMVSIDKQEINTQVFARDGETIVLGGVFH
DTITKGVDKVPLLGDIPILKRLFSRESERHQKRELVIFVTPRIIRSEQPDEIIKPLK

Nucleotide

• Length: 1134 bp

>NTDB_id=379858 FWK48_RS03520 WP_132994602.1 764390..765523(-) (comE) [Histophilus somni strain UOC-KLM-ATR-08]
ATGTTAATTAAAAATTTCTTATATTTCTTTTTGTTCTTATTCACAGTAAGTGTGGAATTATCTGCTAGAGATCCCTTTGA
TAAAAGACAAAGAAGCATAAAAAAAGAGACAAATATACAATTAGATACAAAGGAAAATTTGTCAAAATCGACTAATGAGC
CAAATTTAACGACGACTTCGATCAAATTACATTATGCTAAAGCGGCTGATGTAATGAAATCACTGACTACAGGTCAAGGT
TCATGGCTTTCATCAAATGGAACTTTTAGTTTTGATGAACGAAGTAACTTGCTCTTAATTCAGGATAATCAGGAAACTCT
CAATGCCTTAAAAAAATTAATCAAAGAAATGGATCAACCTATTGAACAAATTGCAATTGAAGCGAGAATTGTAACAATTA
GTGATGAAAATTTAAAAGAATTAGGGGTTCGTTGGGGAATTTTTGAGCCTACAAATAACGCTCATCATCTTTCAGGCAAT
CTAGCGGCAAACGGATTTCAGCATTTAACGGAACAACTTAACGTCAATTTTGCTACTACCGCAACACCTGCAGGTTCTAT
TGCTTTACAAATTGCCAAAATTAATGATCGACTTTTAGACTTAGAACTTACCGCACTTGAACGAGAAAATAATGTAGAAA
TTATTGCAAGCCCTCGTTTACTTACAACGAATAAGCAAAGTGCAAGTATTAAACAAGGAACTGAAATTCCTTATGTTATT
ACCGGCAAGAAATCTGATGAACAGAAAGTAGAGTTTAGAGAAGCAGTTTTAGGATTAGAAGTAACGCCACACATTTCTAA
AGACAATACTATTTTGCTGGATCTCCTTGTAAGCCAAAACTCCCCTGGAAGTCGTATTACTTATGGGCAAAATGAAATGG
TATCTATTGATAAACAAGAAATTAATACTCAAGTTTTTGCACGAGATGGGGAAACAATTGTGTTGGGTGGCGTATTTCAC
GATACAATCACAAAAGGAGTAGATAAAGTACCGTTGTTAGGAGATATACCTATATTAAAAAGACTGTTCAGCCGTGAAAG
TGAAAGACACCAAAAACGTGAATTAGTCATTTTTGTTACCCCAAGGATCATTCGTTCAGAACAACCTGATGAAATAATAA
AACCATTAAAATAG

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (60-123)

• Bacterial type II and III secretion system protein (Secretin) (205-365)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae 86-028NP	75.077	86.207	0.647
comE	Haemophilus influenzae Rd KW20	74.769	86.207	0.645
comE	Glaesserella parasuis strain SC1401	61.587	83.554	0.515
pilQ	Vibrio campbellii strain DS40M4	44.932	96.817	0.435
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	47.205	85.411	0.403
pilQ	Vibrio cholerae strain A1552	47.205	85.411	0.403