Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   HB753_RS06430 Genome accession   NZ_CP050270
Coordinates   1306569..1308803 (-) Length   744 a.a.
NCBI ID   WP_002296251.1    Uniprot ID   -
Organism   Streptococcus mutans strain S4     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1301569..1313803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB753_RS06410 (HB753_06410) sodA 1302358..1302969 (-) 612 WP_002261912.1 superoxide dismutase SodA -
  HB753_RS06415 (HB753_06415) holA 1303116..1304156 (-) 1041 WP_002281296.1 DNA polymerase III subunit delta -
  HB753_RS06425 (HB753_06425) - 1305757..1306383 (-) 627 WP_002264731.1 DUF805 domain-containing protein -
  HB753_RS06430 (HB753_06430) comEC/celB 1306569..1308803 (-) 2235 WP_002296251.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  HB753_RS06435 (HB753_06435) comEA/celA/cilE 1308793..1309473 (-) 681 WP_002267104.1 helix-hairpin-helix domain-containing protein Machinery gene
  HB753_RS06440 (HB753_06440) - 1309613..1310365 (-) 753 WP_002264733.1 lysophospholipid acyltransferase family protein -
  HB753_RS06445 (HB753_06445) - 1310504..1311439 (+) 936 WP_002269713.1 polysaccharide deacetylase family protein -
  HB753_RS06450 (HB753_06450) - 1311528..1312040 (+) 513 WP_002265382.1 HXXEE domain-containing protein -
  HB753_RS06455 (HB753_06455) - 1312086..1313105 (+) 1020 WP_019316272.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 85560.01 Da        Isoelectric Point: 10.0891

>NTDB_id=377660 HB753_RS06430 WP_002296251.1 1306569..1308803(-) (comEC/celB) [Streptococcus mutans strain S4]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSINGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRRRISDANAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=377660 HB753_RS06430 WP_002296251.1 1306569..1308803(-) (comEC/celB) [Streptococcus mutans strain S4]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGCTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTATCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCAGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTCACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTACCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAGAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTGACTTTTGGACAGACTGATAAATGGCGGCGGCGTATCAGTGATGCTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterProScan.

Competence protein (Competence)

(214-460)

Domain of unknown function (DUF4131) (DUF4131)

(30-174)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

51.147

99.597

0.509
  comEC/celB Streptococcus mitis NCTC 12261

51.078

99.731

0.509
  comEC/celB Streptococcus pneumoniae TIGR4

50.672

100

0.507
  comEC/celB Streptococcus pneumoniae Rx1

50

100

0.5
  comEC/celB Streptococcus pneumoniae D39

50

100

0.5
  comEC/celB Streptococcus pneumoniae R6

50

100

0.5
  comEC Lactococcus lactis subsp. cremoris KW2

46.174

100

0.462

Multiple sequence alignment