Detailed information NTG0377477

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: HA248_RS01305
• Genome accession: NZ_CP050175
• Coordinates: 234365..235363 (+)
• Length: 332 a.a.
• NCBI ID: WP_001809468.1
• Uniprot ID: Q8CWU7
• Organism: Streptococcus pneumoniae strain PZ900701590
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 229365..240363

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HA248_RS01285 (HA248_01280)	-	231303..232145 (+)	843	WP_001081167.1	hypothetical protein	-
HA248_RS01290 (HA248_01285)	-	232201..232896 (+)	696	WP_001144904.1	GNAT family N-acetyltransferase	-
HA248_RS01295 (HA248_01290)	-	232908..233324 (+)	417	WP_000628384.1	GNAT family N-acetyltransferase	-
HA248_RS01300 (HA248_01295)	-	234139..234231 (-)	93	WP_000970381.1	type I toxin-antitoxin system Fst family toxin	-
HA248_RS01305 (HA248_01300)	ruvB	234365..235363 (+)	999	WP_001809468.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
HA248_RS01310 (HA248_01305)	-	235344..235916 (+)	573	Protein_258	nucleotidyltransferase family protein	-
HA248_RS01315 (HA248_01310)	-	236147..236905 (+)	759	WP_000466719.1	isoprenyl transferase	-
HA248_RS01320 (HA248_01315)	-	236914..237717 (+)	804	WP_000189857.1	phosphatidate cytidylyltransferase	-
HA248_RS01325 (HA248_01320)	eeP	237739..238998 (+)	1260	WP_033705633.1	RIP metalloprotease RseP	Regulator

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37288.73 Da
• Isoelectric Point: 4.5053

>NTDB_id=377477 HA248_RS01305 WP_001809468.1 234365..235363(+) (ruvB) [Streptococcus pneumoniae strain PZ900701590]
MSRILDNEIMGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKAGDLVAILNELEPGDVLFIDEIHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRVRDFAQIMGNGVID
DIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAK
AYEHLGYEYSEK

Nucleotide

• Length: 999 bp

>NTDB_id=377477 HA248_RS01305 WP_001809468.1 234365..235363(+) (ruvB) [Streptococcus pneumoniae strain PZ900701590]
ATGAGTAGAATTTTAGATAATGAGATAATGGGGGATGAGGAGTTAGTAGAACGCACGCTCCGTCCTCAGTATTTACGTGA
ATATATTGGTCAGGATAAGGTTAAGGATCAGCTTCAGATCTTTATCGAAGCCGCTAAAATGCGGGATGAAGCGCTGGATC
ATGTGCTCTTATTTGGCCCTCCAGGGCTTGGGAAAACAACCATGGCTTTTGTCATTGCCAATGAACTGGGAGTCAATCTC
AAGCAAACGTCTGGTCCTGTTATCGAAAAAGCGGGTGATTTGGTAGCGATTTTGAATGAGTTAGAGCCTGGAGATGTCCT
CTTTATTGACGAGATTCATCGCTTACCCATGTCAGTGGAAGAAGTGCTTTATAGTGCCATGGAGGACTTCTACATCGATA
TTATGATTGGGGCTGGTGAAGGCAGTCGCAGTGTTCATTTGGAGTTGCCTCCTTTTACCTTGATTGGTGCGACGACTCGG
GCTGGTATGCTCTCAAATCCACTACGGGCACGTTTTGGGATTACAGGTCATATGGAGTATTATGCCCATGCTGACTTGAC
AGAAATTGTCGAGCGGACGGCAGATATTTTTGAGATGGAAATCACTCATGAGGCAGCATCTGAGTTGGCCCTACGTAGTC
GTGGAACCCCTCGTATTGCCAATCGTCTCCTCAAGCGCGTGCGCGATTTTGCCCAGATAATGGGGAATGGGGTAATCGAT
GATATTATTACCGATAAGGCTTTGACTATGCTGGATGTTGACCATGAAGGTTTGGACTATGTGGATCAAAAAATCCTTCG
TACCATGATTGAGATGTACAGTGGAGGACCTGTTGGTCTAGGAACTCTTTCTGTCAATATCGCCGAAGAGCGTGAGACAG
TTGAAGACATGTATGAGCCTTACTTGATTCAAAAAGGTTTTATCATGCGGACACGGTCTGGACGGGTGGCGACTGCTAAG
GCATATGAGCACTTAGGTTATGAATACAGTGAAAAATAA

Domains

Predicted by InterProScan.

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: Q8CWU7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	100	100	1
ruvB	Streptococcus pneumoniae D39	100	100	1
ruvB	Streptococcus pneumoniae TIGR4	99.096	100	0.991
ruvB	Bacillus subtilis subsp. subtilis str. 168	60.429	98.193	0.593
ruvB	Helicobacter pylori 26695	50.774	97.289	0.494
ruvB	Synechocystis sp. PCC 6803	49.84	94.277	0.47