Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FP508_RS08085 Genome accession   NZ_CP041998
Coordinates   1599098..1599787 (-) Length   229 a.a.
NCBI ID   WP_185159747.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS7     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1594098..1604787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FP508_RS08065 (FP508_08340) dnaI 1594901..1595803 (-) 903 WP_000843626.1 primosomal protein DnaI -
  FP508_RS08070 (FP508_08345) - 1595800..1596975 (-) 1176 WP_000074512.1 DnaD domain protein -
  FP508_RS08075 (FP508_08350) nrdR 1596975..1597454 (-) 480 WP_001203682.1 transcriptional regulator NrdR -
  FP508_RS08080 (FP508_08355) - 1597603..1599108 (-) 1506 WP_185159746.1 HAMP domain-containing histidine kinase -
  FP508_RS08085 (FP508_08360) covR 1599098..1599787 (-) 690 WP_185159747.1 response regulator transcription factor Regulator
  FP508_RS08090 (FP508_08365) - 1600022..1600555 (-) 534 WP_000927543.1 DUF177 domain-containing protein -
  FP508_RS08095 (FP508_08370) htpX 1600660..1601550 (-) 891 WP_000966817.1 zinc metalloprotease HtpX -
  FP508_RS08100 (FP508_08375) - 1601571..1602125 (-) 555 WP_000537055.1 LemA family protein -
  FP508_RS08105 (FP508_08380) rsmG 1602253..1602966 (+) 714 WP_000188792.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FP508_RS08110 (FP508_08385) - 1602981..1604360 (+) 1380 WP_000680112.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26546.61 Da        Isoelectric Point: 4.9899

>NTDB_id=375326 FP508_RS08085 WP_185159747.1 1599098..1599787(-) (covR) [Streptococcus agalactiae strain GBS7]
MGKKILIIEDEKNLARFVSLELLHEGYDVVVETNGREGLDTALEKDFDLILLDLMLPEMDGFEITRRLQAKKTTYIMMMT
ARDSVMDIVAGLDRGADDYIVKPFAIEELLARVRAIFRRQEIETKTKEKGDSGSFRDLSLNTHNRSAMRGDEEISLTKRE
FDLLNVLMTNMNRVMTREELLEHVWKYDVAAETNVVDVYIRYLRGKIDIPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=375326 FP508_RS08085 WP_185159747.1 1599098..1599787(-) (covR) [Streptococcus agalactiae strain GBS7]
ATGGGTAAAAAGATCTTAATAATCGAAGATGAGAAAAATTTAGCTCGCTTCGTCTCGTTAGAACTACTACATGAAGGATA
TGATGTTGTTGTTGAAACAAACGGTCGTGAAGGATTGGACACAGCATTAGAAAAAGATTTTGATTTGATTCTACTGGATT
TAATGCTTCCAGAGATGGATGGTTTCGAAATCACACGTCGCCTGCAGGCTAAAAAAACAACCTATATCATGATGATGACA
GCACGTGATTCTGTTATGGATATTGTAGCTGGTCTTGATCGTGGAGCAGATGATTATATTGTTAAGCCGTTTGCAATCGA
AGAATTATTAGCACGTGTTAGAGCGATTTTCCGACGCCAAGAAATTGAAACGAAGACAAAAGAAAAAGGTGATAGTGGTA
GTTTCCGTGATTTGTCATTAAATACTCATAATCGTTCAGCGATGCGTGGTGATGAGGAAATTTCACTAACAAAACGTGAA
TTTGATTTGTTGAATGTCTTGATGACAAATATGAATCGTGTTATGACACGAGAAGAGTTGCTAGAACATGTTTGGAAATA
CGATGTGGCAGCAGAGACAAACGTTGTTGATGTTTATATCCGTTACCTAAGAGGTAAAATTGATATCCCAGGTCGTGAAT
CATATATTCAAACTGTTCGCGGAATGGGCTATGTGATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

79.039

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.789

99.563

0.655
  vicR Streptococcus mutans UA159

45.887

100

0.463
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.437

Multiple sequence alignment