Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   FPL13_RS06685 Genome accession   NZ_CP041968
Coordinates   1381892..1382551 (+) Length   219 a.a.
NCBI ID   WP_049512414.1    Uniprot ID   A0A7L8W6B5
Organism   Streptococcus sp. KS 6     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1376892..1387551
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FPL13_RS06650 (FPL13_06735) - 1376904..1377188 (-) 285 WP_049512424.1 DUF3165 family protein -
  FPL13_RS06655 (FPL13_06740) typA 1377248..1379089 (-) 1842 WP_106387848.1 translational GTPase TypA -
  FPL13_RS06660 (FPL13_06745) - 1379256..1379978 (+) 723 WP_049512420.1 16S rRNA pseudouridine(516) synthase -
  FPL13_RS06665 (FPL13_06750) - 1380043..1380199 (-) 157 Protein_1327 group II intron reverse transcriptase/maturase -
  FPL13_RS06670 (FPL13_06755) - 1380339..1380719 (-) 381 WP_049512418.1 rhodanese-like domain-containing protein -
  FPL13_RS06675 (FPL13_06760) - 1380713..1380937 (-) 225 WP_003043479.1 YqgQ family protein -
  FPL13_RS06680 (FPL13_06765) - 1381211..1381738 (-) 528 WP_049512415.1 Dps family protein -
  FPL13_RS06685 (FPL13_06770) cclA/cilC 1381892..1382551 (+) 660 WP_049512414.1 prepilin peptidase Machinery gene
  FPL13_RS06690 (FPL13_06775) trpB 1382711..1383897 (-) 1187 Protein_1332 tryptophan synthase subunit beta -
  FPL13_RS06695 (FPL13_06780) - 1384282..1384812 (-) 531 WP_049512413.1 VanZ family protein -
  FPL13_RS06700 (FPL13_06785) rlmN 1384805..1385887 (-) 1083 WP_049512411.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  FPL13_RS06705 (FPL13_06790) - 1385926..1386489 (-) 564 WP_049512409.1 YutD family protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24825.23 Da        Isoelectric Point: 8.2951

>NTDB_id=375016 FPL13_RS06685 WP_049512414.1 1381892..1382551(+) (cclA/cilC) [Streptococcus sp. KS 6]
MIHFYFFLVGSIVASFLGLVVDRFPEQSIISPSSHCNACGQKLAPRDLVPVLSQLINRLRCRFCQSKIPIRYLILELVGG
LLFLATSLSYLNISQLVLLIMGITLALYDQREQEYPILIWLFFHLLLLFLVGFNLLMISFLALGIVAFFFDLRIGAGDFL
FLSSCSTVFKLTEILWLIQIASLVGLCLFCLKKRKDRIAFVPCLLIGVIVLLLYELLLP

Nucleotide


Download         Length: 660 bp        

>NTDB_id=375016 FPL13_RS06685 WP_049512414.1 1381892..1382551(+) (cclA/cilC) [Streptococcus sp. KS 6]
ATGATTCATTTTTATTTTTTCTTGGTTGGAAGTATTGTGGCTTCTTTTTTAGGACTGGTTGTTGATCGCTTTCCTGAACA
ATCTATTATCAGTCCTTCCAGTCATTGTAATGCTTGTGGACAGAAATTAGCACCTCGTGATTTAGTCCCTGTCCTTTCTC
AGCTTATCAATCGACTGCGCTGTCGGTTTTGTCAGTCAAAAATTCCCATTCGCTACTTGATATTAGAGTTGGTAGGTGGT
TTACTCTTTCTCGCAACTTCCTTAAGCTACTTAAATATCAGCCAGCTTGTCTTGCTCATAATGGGAATTACACTAGCTCT
TTATGATCAAAGAGAACAGGAATATCCTATCCTCATTTGGTTGTTCTTTCATCTTCTTCTCCTATTTTTGGTAGGTTTTA
ATCTTCTAATGATTAGTTTTTTAGCCCTTGGAATAGTAGCTTTTTTCTTTGACTTACGAATTGGCGCAGGAGACTTTCTT
TTTCTATCTTCTTGTTCAACTGTTTTCAAGTTGACAGAGATTCTTTGGCTGATTCAAATTGCCAGCTTAGTGGGATTATG
TCTCTTTTGCTTAAAAAAGAGAAAAGACAGGATAGCTTTCGTTCCCTGTCTTTTGATTGGAGTGATTGTTCTGCTTCTGT
ACGAACTGTTGCTTCCATAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L8W6B5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

56.881

99.543

0.566
  cclA/cilC Streptococcus pneumoniae Rx1

56.881

99.543

0.566
  cclA/cilC Streptococcus pneumoniae D39

56.881

99.543

0.566
  cclA/cilC Streptococcus pneumoniae R6

56.881

99.543

0.566
  cclA/cilC Streptococcus mitis NCTC 12261

56.422

99.543

0.562
  cclA/cilC Streptococcus pneumoniae TIGR4

55.963

99.543

0.557

Multiple sequence alignment