Detailed information NTG0371765

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: G5S46_RS09870
• Genome accession: NZ_CP048929
• Coordinates: 1895728..1896954 (+)
• Length: 408 a.a.
• NCBI ID: WP_003690199.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain CT213
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1890728..1901954

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G5S46_RS09845 (G5S46_09675)	dksA	1891904..1892320 (-)	417	WP_003692108.1	RNA polymerase-binding protein DksA	-
G5S46_RS09850 (G5S46_09680)	proC	1892468..1893259 (-)	792	WP_003696395.1	pyrroline-5-carboxylate reductase	-
G5S46_RS09855 (G5S46_09685)	-	1893308..1893715 (-)	408	WP_003690202.1	hypothetical protein	-
G5S46_RS09860 (G5S46_09690)	-	1893715..1894401 (-)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
G5S46_RS09865 (G5S46_09695)	pilT	1894521..1895564 (+)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
G5S46_RS09870 (G5S46_09700)	pilU	1895728..1896954 (+)	1227	WP_003690199.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
G5S46_RS09875 (G5S46_09705)	yccS	1897071..1899221 (+)	2151	WP_050169463.1	YccS family putative transporter	-
G5S46_RS09880 (G5S46_09710)	-	1900085..1900369 (-)	285	WP_003692093.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45672.29 Da
• Isoelectric Point: 7.3203

>NTDB_id=371765 G5S46_RS09870 WP_003690199.1 1895728..1896954(+) (pilU) [Neisseria gonorrhoeae strain CT213]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=371765 G5S46_RS09870 WP_003690199.1 1895728..1896954(+) (pilU) [Neisseria gonorrhoeae strain CT213]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387