Detailed information    

insolico Bioinformatically predicted

Overview


Name   ideA   Type   Regulator
Locus tag   FKM99_RS22315 Genome accession   NZ_CP041202
Coordinates   2687317..2688000 (+) Length   227 a.a.
NCBI ID   WP_077671779.1    Uniprot ID   -
Organism   Vibrio parahaemolyticus strain Vb0624     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2664245..2698676 2687317..2688000 within 0


Gene organization within MGE regions


Location: 2664245..2698676
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FKM99_RS22195 (FKM99_22195) - 2664245..2665114 (+) 870 WP_077671794.1 hypothetical protein -
  FKM99_RS22200 (FKM99_22200) - 2665101..2665763 (+) 663 WP_007105460.1 DUF6475 domain-containing protein -
  FKM99_RS22205 (FKM99_22205) - 2665750..2666298 (+) 549 WP_025610846.1 lytic transglycosylase domain-containing protein -
  FKM99_RS22210 (FKM99_22210) - 2666295..2666594 (+) 300 WP_000210563.1 flagellar transcriptional regulator FlhD -
  FKM99_RS22215 (FKM99_22215) - 2666591..2667124 (+) 534 WP_024008816.1 FlhC family transcriptional regulator -
  FKM99_RS22220 (FKM99_22220) eexS 2667179..2667610 (+) 432 WP_077671793.1 entry exclusion protein EexS -
  FKM99_RS22225 (FKM99_22225) - 2667643..2671212 (-) 3570 WP_077671792.1 conjugal transfer protein TraG N-terminal domain-containing protein -
  FKM99_RS22230 (FKM99_22230) - 2671216..2672604 (-) 1389 WP_077671791.1 conjugal transfer protein TraH -
  FKM99_RS22235 (FKM99_22235) - 2672607..2673551 (-) 945 WP_077671790.1 thioredoxin family protein -
  FKM99_RS22240 (FKM99_22240) - 2673755..2674819 (-) 1065 WP_077671789.1 hypothetical protein -
  FKM99_RS22245 (FKM99_22245) - 2675182..2675889 (-) 708 WP_077671788.1 hypothetical protein -
  FKM99_RS22250 (FKM99_22250) - 2675979..2677046 (-) 1068 WP_077671787.1 primase-helicase zinc-binding domain-containing protein -
  FKM99_RS22255 (FKM99_22255) - 2677138..2677479 (-) 342 WP_077671786.1 plasmid-related protein -
  FKM99_RS22260 (FKM99_22260) radC 2677479..2677976 (-) 498 WP_077671785.1 DNA repair protein RadC -
  FKM99_RS22265 (FKM99_22265) - 2678061..2679716 (-) 1656 WP_077671784.1 VWA domain-containing protein -
  FKM99_RS22270 (FKM99_22270) - 2679786..2680226 (-) 441 WP_032469941.1 hypothetical protein -
  FKM99_RS22275 (FKM99_22275) - 2680288..2681241 (-) 954 WP_077671783.1 DUF3150 domain-containing protein -
  FKM99_RS22280 (FKM99_22280) - 2681340..2682107 (-) 768 WP_077671782.1 WGR domain-containing protein -
  FKM99_RS22285 (FKM99_22285) - 2682107..2683066 (-) 960 WP_001959209.1 AAA family ATPase -
  FKM99_RS22290 (FKM99_22290) - 2683276..2684292 (-) 1017 WP_077671781.1 YqaJ viral recombinase family protein -
  FKM99_RS26920 - 2684354..2684497 (-) 144 WP_169674712.1 hypothetical protein -
  FKM99_RS22295 (FKM99_22295) bet 2684579..2685397 (-) 819 WP_000414662.1 phage recombination protein Bet -
  FKM99_RS22300 (FKM99_22300) - 2685477..2685896 (-) 420 WP_141180370.1 single-stranded DNA-binding protein -
  FKM99_RS22305 (FKM99_22305) - 2685912..2686238 (-) 327 WP_141180371.1 plasmid-related protein -
  FKM99_RS22310 (FKM99_22310) - 2686606..2687208 (+) 603 WP_032081055.1 hypothetical protein -
  FKM99_RS22315 (FKM99_22315) ideA 2687317..2688000 (+) 684 WP_077671779.1 endonuclease Regulator
  FKM99_RS22320 (FKM99_22320) - 2688172..2689146 (-) 975 WP_077671778.1 caspase family protein -
  FKM99_RS22325 (FKM99_22325) - 2689157..2689540 (-) 384 WP_077671777.1 TIR domain-containing protein -
  FKM99_RS22335 (FKM99_22335) - 2689744..2690952 (+) 1209 Protein_2435 IS4-like element ISVsa5 family transposase -
  FKM99_RS27340 (FKM99_22340) - 2690962..2691087 (-) 126 WP_001303004.1 LysR family transcriptional regulator -
  FKM99_RS22345 (FKM99_22345) gltS 2691318..2692523 (-) 1206 WP_000599531.1 sodium/glutamate symporter -
  FKM99_RS22350 (FKM99_22350) - 2692967..2693287 (+) 321 WP_000562370.1 antibiotic biosynthesis monooxygenase -
  FKM99_RS22355 (FKM99_22355) - 2693280..2693666 (+) 387 WP_000460651.1 hypothetical protein -
  FKM99_RS22360 (FKM99_22360) - 2693674..2694360 (+) 687 WP_001284954.1 helix-turn-helix transcriptional regulator -
  FKM99_RS22365 (FKM99_22365) tetR(B) 2694338..2694961 (-) 624 WP_000088605.1 tetracycline resistance transcriptional repressor TetR(B) -
  FKM99_RS22370 (FKM99_22370) tet(B) 2695043..2696248 (+) 1206 WP_010446567.1 tetracycline efflux MFS transporter Tet(B) -
  FKM99_RS22375 (FKM99_22375) tetC 2696361..2696954 (-) 594 WP_000428546.1 tetracyline resistance-associated transcriptional repressor TetC -
  FKM99_RS22380 (FKM99_22380) - 2697042..2697458 (+) 417 WP_000275180.1 helix-turn-helix domain-containing protein -
  FKM99_RS22385 (FKM99_22385) - 2697468..2698676 (-) 1209 Protein_2445 IS4-like element ISVsa5 family transposase -

Sequence


Protein


Download         Length: 227 a.a.        Molecular weight: 26505.62 Da        Isoelectric Point: 7.1838

>NTDB_id=370457 FKM99_RS22315 WP_077671779.1 2687317..2688000(+) (ideA) [Vibrio parahaemolyticus strain Vb0624]
MNRTNFFVTFFIALFAIPAIAEHPTSFSQAKRFAREIYQDNQSTFYCGCSYNNDGAIDAASCGYEPRKQPKRGERLEWEH
VVSAWEIGHQRQCWQNGGRRNCEKNDPEFSKMVSDLHNLVPSVGELNGDRSNFRFGMIPNEPRAYGQCDFEVDFKDRRAE
PPANRQGDIARIYFYMRDQYGLRLSRQQTQLFEAWSRMDPVDEWEKVRDFKIKSILGKSNCYVSDSC

Nucleotide


Download         Length: 684 bp        

>NTDB_id=370457 FKM99_RS22315 WP_077671779.1 2687317..2688000(+) (ideA) [Vibrio parahaemolyticus strain Vb0624]
ATGAATAGAACTAATTTTTTCGTTACTTTCTTTATAGCGCTGTTCGCTATACCTGCAATTGCAGAACACCCCACATCGTT
CAGTCAGGCAAAACGATTTGCCCGTGAAATTTACCAAGACAACCAGAGTACGTTTTACTGTGGATGTAGCTATAACAATG
ATGGTGCGATTGATGCTGCATCTTGCGGATATGAACCAAGGAAGCAACCGAAACGAGGAGAACGCTTAGAGTGGGAGCAC
GTTGTCTCAGCATGGGAAATTGGCCATCAACGCCAATGCTGGCAAAACGGTGGACGTCGGAACTGCGAAAAGAATGATCC
TGAGTTTTCTAAAATGGTTTCGGATCTCCATAACCTCGTACCATCAGTAGGTGAGCTCAACGGGGATAGATCAAATTTTC
GATTTGGCATGATTCCGAACGAACCAAGGGCCTATGGTCAATGTGATTTCGAAGTTGATTTCAAAGACCGCCGAGCAGAA
CCACCAGCTAACCGTCAGGGTGATATTGCTAGAATTTATTTCTACATGCGAGATCAATACGGCCTAAGACTAAGCAGGCA
ACAAACTCAGCTTTTTGAAGCTTGGTCAAGAATGGACCCTGTTGACGAATGGGAAAAAGTGCGTGATTTTAAGATTAAAA
GTATTCTAGGTAAATCAAATTGCTATGTATCAGATAGCTGTTAA

Domains


Predicted by InterproScan.

(41-226)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ideA Vibrio cholerae O1 str. 2010EL-1786

95.154

100

0.952

  dns Aliivibrio fischeri ES114

50.87

100

0.515

  dns Vibrio parahaemolyticus RIMD 2210633

51.092

100

0.515

  dns Vibrio cholerae strain A1552

50.667

99.119

0.502

  dns Campylobacter jejuni RM1221

37.778

99.119

0.374


Multiple sequence alignment