Detailed information NTG0368845

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: FIU24_RS05855
• Genome accession: NZ_CP041013
• Coordinates: 1244784..1246121 (-)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain FDAARGOS_610
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1239784..1251121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU24_RS05825 (FIU24_05825)	pilX	1240435..1241022 (-)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-
FIU24_RS05830 (FIU24_05830)	pilW	1241019..1241843 (-)	825	WP_004352757.1	type 4a pilus minor pilin PilW	-
FIU24_RS05835 (FIU24_05835)	pilV	1241840..1242397 (-)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
FIU24_RS05840 (FIU24_05840)	-	1242388..1242894 (-)	507	WP_003102598.1	GspH/FimT family pseudopilin	-
FIU24_RS05845 (FIU24_05845)	-	1243000..1243509 (-)	510	WP_003161431.1	GspH/FimT family pseudopilin	-
FIU24_RS05850 (FIU24_05850)	thiO	1243644..1244738 (+)	1095	WP_003119424.1	glycine oxidase ThiO	-
FIU24_RS05855 (FIU24_05855)	pilR	1244784..1246121 (-)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
FIU24_RS05860 (FIU24_05860)	pilS	1246136..1247728 (-)	1593	WP_003094692.1	two-component system sensor histidine kinase PilS	Regulator
FIU24_RS05865 (FIU24_05865)	-	1247718..1247963 (-)	246	WP_003102591.1	PP0621 family protein	-
FIU24_RS05870 (FIU24_05870)	-	1248120..1249145 (-)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
FIU24_RS05875 (FIU24_05875)	rluD	1249291..1250253 (+)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
FIU24_RS05880 (FIU24_05880)	pgeF	1250250..1250978 (+)	729	WP_004352764.1	peptidoglycan editing factor PgeF	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=368845 FIU24_RS05855 WP_003094694.1 1244784..1246121(-) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_610]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=368845 FIU24_RS05855 WP_003094694.1 1244784..1246121(-) (pilR) [Pseudomonas aeruginosa strain FDAARGOS_610]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384