Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FIU13_RS07085 Genome accession   NZ_CP040997
Coordinates   1352384..1353070 (+) Length   228 a.a.
NCBI ID   WP_002991052.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain FDAARGOS_774     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1347384..1358070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FIU13_RS07060 (FIU13_07060) ktrB 1347526..1348902 (-) 1377 WP_228549910.1 TrkH family potassium uptake protein -
  FIU13_RS07065 (FIU13_07065) rsmG 1348987..1349700 (-) 714 WP_010921904.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  FIU13_RS07070 (FIU13_07070) - 1349850..1350407 (+) 558 WP_002985956.1 LemA family protein -
  FIU13_RS07075 (FIU13_07075) htpX 1350454..1351350 (+) 897 WP_002985953.1 zinc metalloprotease HtpX -
  FIU13_RS07080 (FIU13_07080) - 1351584..1352117 (+) 534 WP_011054200.1 YceD family protein -
  FIU13_RS07085 (FIU13_07085) covR 1352384..1353070 (+) 687 WP_002991052.1 two-component system response regulator CovR Regulator
  FIU13_RS07090 (FIU13_07090) covS 1353076..1354579 (+) 1504 Protein_1307 two-component system sensor histidine kinase CovS -
  FIU13_RS07095 (FIU13_07095) nrdR 1354794..1355288 (+) 495 WP_002985941.1 transcriptional regulator NrdR -
  FIU13_RS07100 (FIU13_07100) - 1355272..1356447 (+) 1176 WP_002991019.1 replication initiation and membrane attachment family protein -
  FIU13_RS07105 (FIU13_07105) dnaI 1356448..1357350 (+) 903 WP_002991016.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26618.70 Da        Isoelectric Point: 4.6586

>NTDB_id=368624 FIU13_RS07085 WP_002991052.1 1352384..1353070(+) (covR) [Streptococcus pyogenes strain FDAARGOS_774]
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEVNGREGLETALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=368624 FIU13_RS07085 WP_002991052.1 1352384..1353070(+) (covR) [Streptococcus pyogenes strain FDAARGOS_774]
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGTCAATGGTCGTGAAGGGTTAGAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGCATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.966

100

0.447
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.425

Multiple sequence alignment