Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FHI56_RS08025 Genome accession   NZ_CP040804
Coordinates   1398367..1399782 (-) Length   471 a.a.
NCBI ID   WP_045772383.1    Uniprot ID   A0AB37CP29
Organism   Streptococcus salivarius strain LAB813     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1393367..1404782
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS07995 (FHI56_07995) - 1394004..1394402 (-) 399 WP_118058062.1 cytidine deaminase -
  FHI56_RS08000 (FHI56_08000) deoC 1394389..1395051 (-) 663 WP_004182396.1 deoxyribose-phosphate aldolase -
  FHI56_RS08005 (FHI56_08005) - 1395086..1396363 (-) 1278 WP_118058063.1 pyrimidine-nucleoside phosphorylase -
  FHI56_RS08010 (FHI56_08010) - 1396360..1396950 (-) 591 WP_004182394.1 class I SAM-dependent methyltransferase -
  FHI56_RS08015 (FHI56_08015) coaA 1397063..1397983 (+) 921 WP_004182393.1 type I pantothenate kinase -
  FHI56_RS08020 (FHI56_08020) rpsT 1398053..1398289 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  FHI56_RS08025 (FHI56_08025) ciaH 1398367..1399782 (-) 1416 WP_045772383.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FHI56_RS08030 (FHI56_08030) ciaR 1399772..1400446 (-) 675 WP_002891134.1 response regulator transcription factor Regulator
  FHI56_RS08035 (FHI56_08035) - 1400645..1402315 (-) 1671 WP_149561360.1 formate--tetrahydrofolate ligase -
  FHI56_RS08040 (FHI56_08040) - 1402521..1403204 (+) 684 WP_004182113.1 phosphopantothenate--cysteine ligase -
  FHI56_RS08045 (FHI56_08045) coaC 1403197..1403742 (+) 546 WP_004182014.1 phosphopantothenoylcysteine decarboxylase -
  FHI56_RS08050 (FHI56_08050) - 1403771..1404343 (+) 573 WP_004182105.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53504.28 Da        Isoelectric Point: 8.7661

>NTDB_id=367359 FHI56_RS08025 WP_045772383.1 1398367..1399782(-) (ciaH) [Streptococcus salivarius strain LAB813]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVIALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=367359 FHI56_RS08025 WP_045772383.1 1398367..1399782(-) (ciaH) [Streptococcus salivarius strain LAB813]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGTGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTCAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCTGTTGCGGCAAACACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTAGTCGTCCAATCCAAACTGATAAAACGCTATTGAAACAGTTAATGACCATTTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTATAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment