Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   FHI56_RS04340 Genome accession   NZ_CP040804
Coordinates   636518..637216 (+) Length   232 a.a.
NCBI ID   WP_013991034.1    Uniprot ID   A0AAP3Q627
Organism   Streptococcus salivarius strain LAB813     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 631518..642216
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHI56_RS04315 (FHI56_04315) - 631861..633447 (+) 1587 WP_004183188.1 DEAD/DEAH box helicase -
  FHI56_RS04320 (FHI56_04320) - 633503..633772 (-) 270 WP_013991038.1 GIY-YIG nuclease family protein -
  FHI56_RS04325 (FHI56_04325) - 633776..634540 (-) 765 WP_013991037.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  FHI56_RS04330 (FHI56_04330) - 634590..635525 (-) 936 WP_045002039.1 polysaccharide deacetylase family protein -
  FHI56_RS04335 (FHI56_04335) - 635655..636410 (+) 756 WP_048790321.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FHI56_RS04340 (FHI56_04340) comEA 636518..637216 (+) 699 WP_013991034.1 helix-hairpin-helix domain-containing protein Machinery gene
  FHI56_RS04345 (FHI56_04345) comEC/celB 637206..639446 (+) 2241 WP_013991033.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FHI56_RS04350 (FHI56_04350) - 639532..640794 (+) 1263 WP_013991032.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  FHI56_RS04355 (FHI56_04355) - 640860..641405 (+) 546 WP_013991031.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 24503.36 Da        Isoelectric Point: 4.4966

>NTDB_id=367344 FHI56_RS04340 WP_013991034.1 636518..637216(+) (comEA) [Streptococcus salivarius strain LAB813]
MKEKILAYVKDNCLFVSVIAVLMVIFCFFLWMTYCAGNSMEAETSYTDVTALSTSSSSKQSSQSLSEASSQSKTEGSEKD
ESKVTVDVKGAVANPGVYTLKASARVTDAIKAAGGMTEDADAKSVNLAASLSDEEVVYVATKDENLSVLGQSGTGQVSDK
GGQTSAKDGKINLNTATSEELQTISGIGAKRAEDIIAYRESHGGFQSIDDLKNVSGIGEKTLDKIRESLYVA

Nucleotide


Download         Length: 699 bp        

>NTDB_id=367344 FHI56_RS04340 WP_013991034.1 636518..637216(+) (comEA) [Streptococcus salivarius strain LAB813]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATTGTCTGTTTGTGAGTGTTATTGCTGTACTGATGGTGATTTTTTG
CTTCTTCCTATGGATGACTTACTGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CCTCCTCCTCCTCCAAACAAAGCTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACTGAAGGAAGTGAAAAGGAT
GAGTCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGCTAATCCGGGTGTTTATACCTTAAAAGCAAGCGCTAGGGTGAC
TGATGCCATCAAAGCCGCTGGGGGAATGACTGAGGATGCGGATGCTAAGAGTGTTAACTTAGCTGCAAGCTTGTCAGACG
AAGAGGTTGTCTATGTGGCAACTAAGGATGAAAACCTCTCTGTTCTTGGTCAATCAGGAACTGGTCAGGTCTCTGATAAA
GGAGGGCAAACTAGTGCTAAGGATGGCAAAATTAACTTAAATACAGCGACCTCAGAGGAGTTGCAAACCATTTCTGGGAT
TGGAGCTAAGCGTGCTGAGGATATCATTGCCTATCGTGAAAGTCATGGTGGCTTTCAATCCATAGATGACTTGAAAAATG
TCTCAGGAATTGGTGAAAAAACTTTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(169-229)

SLBB domain (SLBB)

(86-139)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

87.5

100

0.875
  comEA/celA/cilE Streptococcus mitis SK321

40

99.138

0.397
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.565

99.138

0.392

Multiple sequence alignment