Detailed information NTG0367345

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: FHI56_RS04345
• Genome accession: NZ_CP040804
• Coordinates: 637206..639446 (+)
• Length: 746 a.a.
• NCBI ID: WP_013991033.1
• Uniprot ID: A0AAP3Q6Q7
• Organism: Streptococcus salivarius strain LAB813
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 632206..644446

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FHI56_RS04320 (FHI56_04320)	-	633503..633772 (-)	270	WP_013991038.1	GIY-YIG nuclease family protein	-
FHI56_RS04325 (FHI56_04325)	-	633776..634540 (-)	765	WP_013991037.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FHI56_RS04330 (FHI56_04330)	-	634590..635525 (-)	936	WP_045002039.1	polysaccharide deacetylase family protein	-
FHI56_RS04335 (FHI56_04335)	-	635655..636410 (+)	756	WP_048790321.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
FHI56_RS04340 (FHI56_04340)	comEA	636518..637216 (+)	699	WP_013991034.1	helix-hairpin-helix domain-containing protein	Machinery gene
FHI56_RS04345 (FHI56_04345)	comEC/celB	637206..639446 (+)	2241	WP_013991033.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FHI56_RS04350 (FHI56_04350)	-	639532..640794 (+)	1263	WP_013991032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FHI56_RS04355 (FHI56_04355)	-	640860..641405 (+)	546	WP_013991031.1	GNAT family N-acetyltransferase	-
FHI56_RS04360 (FHI56_04360)	spxR	641398..642678 (+)	1281	WP_004183175.1	CBS-HotDog domain-containing transcription factor SpxR	-
FHI56_RS04365 (FHI56_04365)	-	642722..643582 (+)	861	WP_004183173.1	methionyl aminopeptidase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84531.46 Da
• Isoelectric Point: 9.8651

>NTDB_id=367345 FHI56_RS04345 WP_013991033.1 637206..639446(+) (comEC/celB) [Streptococcus salivarius strain LAB813]
MWLKKAPINLFSLALLIAALYFTVFVTNVYAIGTFVFLMVCFLKHHWKNKAALKLVGIVGSFFLVYFLFLHHKATIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRMAQIERLDYVVSQKSLSPLAFFHQLRRRALVHIQTHFPSPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICMSLVLSLGILPFLTYYYGTFQPVSLILTAIFSIVFDNFLLPVLT
VFFALSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLLQFSLMIAVLVMLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVHTLKAGDKLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETLERFKQRH
IKVLRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=367345 FHI56_RS04345 WP_013991033.1 637206..639446(+) (comEC/celB) [Streptococcus salivarius strain LAB813]
ATGTGGCTTAAAAAGGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTACGGTTTTTGTCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTTATGGTCTGTTTTTTGAAACATCATTGGAAGAATAAGGCTGCCCTAA
AGTTGGTGGGAATTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTACACCACAAAGCTACCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGTTATCGGTTAATGGTGAGCAATTATCAGCTATCGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CGCTGGTATTAAAGGGGAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTCAATTATCAGTCTTAT
CTAGCCAGCCAAGGTATTTATCGAATGGCTCAGATTGAGCGCTTGGATTATGTGGTGTCTCAAAAATCTCTATCTCCCTT
AGCTTTTTTCCATCAATTGAGGAGAAGGGCTTTGGTTCATATCCAGACACATTTTCCTAGTCCTATGAGACACTATATGA
CAGGCCTACTCTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGTCAGCTTTACACAAGCCTAGGTATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTACCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCC
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGAATAACCTTACTTCTATTGTTTCTCTTT
TTACCTCATTTTCTTTTAACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCTTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTATGAGCTTGGTATTGAGTCTTGGGATTTTGCCTTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATATTTTCCATAGTCTTTGATAACTTTCTCTTGCCTGTCTTGACG
GTCTTCTTTGCCCTTTCAGGACTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCTTGGATAGGCCAGCCATTAATTTTAGGGAAACCTAGTTTGTTACAGTTTAGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGTTCAAAGGAAAAATGGCAGGAGGGGAGCCAGACGAGCAATG
CAGAGAAAACCTTGATTCCCTATCTACAGGCTAGAGGAGTGTCTCAAATTGATCACCTGGTCCTGACGCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGGCCAAGAGGTTTAAGATTAAGGAAATCTGTGTCAGTCAGGGGGCTTTGACTAA
ACCTAGTTTTGTTAAAAGACTTCGGACCTTAAAACGACCAGTTCACACTCTAAAGGCTGGCGACAAATTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAACGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTTTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAGCTGATGGCCAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGCTCATCGTCTGAAGCTTTTTTGGATCAGTTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACATTAGAACGTTTTAAGCAACGTCAC
ATTAAGGTTTTACGAACAGATAAAGACGGAGCCATACGTTTTAAGGGTTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-169)

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.529	100	0.487
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae Rx1	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae D39	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae R6	46.658	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	46.524	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.649	99.196	0.433