Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FDP16_RS06895 Genome accession   NZ_CP040798
Coordinates   1357638..1359029 (-) Length   463 a.a.
NCBI ID   WP_176799090.1    Uniprot ID   A0A7H8V1L6
Organism   Streptococcus sanguinis strain CGMH058     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1352638..1364029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS06875 (FDP16_07160) - 1353230..1354320 (+) 1091 Protein_1339 DEAD/DEAH box helicase -
  FDP16_RS06880 (FDP16_07165) - 1354409..1355806 (-) 1398 WP_176799088.1 polysaccharide deacetylase family protein -
  FDP16_RS06885 (FDP16_07170) - 1355868..1356254 (-) 387 WP_002895748.1 VOC family protein -
  FDP16_RS06895 (FDP16_07180) ciaH 1357638..1359029 (-) 1392 WP_176799090.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FDP16_RS06900 (FDP16_07185) ciaR 1359019..1359693 (-) 675 WP_176799091.1 response regulator transcription factor Regulator
  FDP16_RS06905 (FDP16_07190) - 1359799..1360281 (-) 483 WP_176799092.1 hypothetical protein -
  FDP16_RS06910 (FDP16_07195) - 1360590..1363131 (-) 2542 Protein_1346 M1 family metallopeptidase -
  FDP16_RS06915 (FDP16_07200) - 1363297..1363623 (-) 327 WP_176799093.1 hypothetical protein -
  FDP16_RS06920 (FDP16_07205) - 1363632..1363928 (-) 297 WP_176799094.1 hypothetical protein -

Sequence

Protein


Download         Length: 463 a.a.        Molecular weight: 52511.80 Da        Isoelectric Point: 8.8401

>NTDB_id=367224 FDP16_RS06895 WP_176799090.1 1357638..1359029(-) (ciaH) [Streptococcus sanguinis strain CGMH058]
MLNKIKKTFYADDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTSVDENLKNLSNNPSSVADLAYRTTGQQSDPSNKVN
TKSPKSSKEPDGDPNEESKSDNLTTPNVSSNTFALLLDDNYKNISTSKSDGFLDFNSLDFNKSYLNQIKEIVIGNSFGQT
ESYRAYLFDIDPNNEYPDIKYAVVMTSISQLEQTSGKHEQLIVMVMVSFWGISLIASIYLARMSVKPLLESIQKQKAFVE
NASHELRTPLAVLQSRLETLFRKPEATIMQSSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPQYGEVEPEFFDTTFAN
YCIIARENKKTFHSENMIKHPIVTDQILLKQLMTILFDNAIKYTDDDGEISVTAASSDRYLIFRVADNGPGISNEDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAKQIVDAFKGTIYAKDNKPKGTVFEVKLLLKETKKRSVK

Nucleotide


Download         Length: 1392 bp        

>NTDB_id=367224 FDP16_RS06895 WP_176799090.1 1357638..1359029(-) (ciaH) [Streptococcus sanguinis strain CGMH058]
ATGCTGAATAAAATCAAGAAGACCTTTTATGCGGATGATTTCTCTTATTTCATTCGCTATTTTGGGTTATTTACATTAAT
CTTCTCAGCCATGACCTTGATTATTATTCAGGTTATGCGTTCCAGCCTTTATACGTCAGTTGATGAAAATCTGAAAAACC
TGAGTAATAATCCTAGTTCGGTAGCAGATTTGGCCTATCGGACGACAGGTCAGCAGTCTGATCCTAGCAATAAGGTCAAC
ACTAAAAGTCCTAAAAGTAGTAAAGAGCCAGATGGCGATCCAAACGAAGAGTCTAAGTCTGACAATCTGACGACGCCAAA
TGTTAGTTCTAACACTTTCGCCCTGCTTTTGGATGATAATTATAAAAATATTTCCACTAGCAAGAGCGATGGCTTTCTGG
ACTTTAACTCGCTGGACTTTAACAAGTCCTATCTGAATCAGATCAAGGAAATTGTAATTGGCAACAGCTTTGGCCAGACA
GAAAGCTATCGGGCTTATCTCTTTGATATTGACCCCAATAATGAATATCCAGATATTAAGTACGCTGTGGTCATGACTAG
CATCAGCCAGCTGGAGCAAACTAGCGGCAAGCATGAGCAGTTGATTGTCATGGTTATGGTCAGCTTTTGGGGTATTTCCC
TGATTGCCAGTATTTATCTGGCTCGGATGAGTGTTAAGCCCTTGCTGGAAAGTATCCAGAAGCAGAAGGCTTTCGTGGAA
AATGCCAGTCATGAACTGCGGACACCTTTGGCTGTTTTGCAGAGCCGCTTAGAAACGCTCTTTCGTAAGCCTGAAGCAAC
AATTATGCAGAGCAGTGAAAATATCGCTTCTAGCTTGGATGAAGTACGCAATATGCGTTTGCTGACGACCAATCTTCTCA
ATCTGGCTCGTCGTGATGATGGTATCAAGCCCCAATATGGTGAAGTCGAACCGGAATTTTTTGATACGACCTTTGCTAAT
TACTGCATTATCGCAAGGGAGAATAAAAAAACTTTTCATTCGGAAAATATGATCAAGCACCCTATTGTGACAGATCAAAT
TTTGCTCAAGCAGCTGATGACCATCCTGTTTGACAATGCTATCAAGTACACAGATGATGACGGCGAAATCAGTGTCACGG
CTGCTTCAAGCGATCGTTATCTCATCTTTCGGGTAGCAGATAATGGACCTGGTATCAGCAACGAAGATAAGAAGAAGATT
TTTGATCGCTTTTATCGGGTTGACAAGGCTCGGACCCGTCAGAAAGGTGGCTTTGGTCTGGGGCTTTCTCTGGCCAAGCA
GATTGTCGATGCTTTCAAGGGCACTATTTATGCCAAGGACAACAAACCAAAAGGTACGGTCTTTGAAGTTAAACTGCTAC
TGAAGGAAACGAAAAAGCGCTCTGTTAAATAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(236-301)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(344-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

61.171

99.568

0.609
  ciaH Streptococcus pneumoniae D39

61.171

99.568

0.609
  ciaH Streptococcus pneumoniae R6

61.171

99.568

0.609
  ciaH Streptococcus pneumoniae TIGR4

61.171

99.568

0.609
  ciaH Streptococcus mutans UA159

52.851

98.488

0.521

Multiple sequence alignment