Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   FDP16_RS03975 Genome accession   NZ_CP040798
Coordinates   767340..768689 (+) Length   449 a.a.
NCBI ID   WP_125331413.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain CGMH058     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 762340..773689
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS03945 (FDP16_04095) - 762847..763245 (-) 399 WP_176798652.1 hypothetical protein -
  FDP16_RS03950 (FDP16_04100) - 763355..764014 (-) 660 WP_002912899.1 amino acid ABC transporter permease -
  FDP16_RS03955 (FDP16_04105) - 764025..764705 (-) 681 WP_009659278.1 amino acid ABC transporter permease -
  FDP16_RS03960 (FDP16_04110) - 764718..765530 (-) 813 WP_176798653.1 transporter substrate-binding domain-containing protein -
  FDP16_RS03965 (FDP16_04115) - 765545..766306 (-) 762 WP_176798654.1 amino acid ABC transporter ATP-binding protein -
  FDP16_RS03970 (FDP16_04120) micA 766646..767347 (+) 702 WP_176798655.1 response regulator YycF Regulator
  FDP16_RS03975 (FDP16_04125) micB 767340..768689 (+) 1350 WP_125331413.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FDP16_RS03980 (FDP16_04130) vicX 768699..769499 (+) 801 WP_176798656.1 MBL fold metallo-hydrolase Regulator
  FDP16_RS03985 (FDP16_04135) - 769591..769950 (+) 360 WP_176798657.1 YbaN family protein -
  FDP16_RS03990 (FDP16_04140) rnc 770072..770770 (+) 699 WP_002903151.1 ribonuclease III -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50961.83 Da        Isoelectric Point: 4.3896

>NTDB_id=367216 FDP16_RS03975 WP_125331413.1 767340..768689(+) (micB) [Streptococcus sanguinis strain CGMH058]
MIEAIKQFVVSADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDDI

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=367216 FDP16_RS03975 WP_125331413.1 767340..768689(+) (micB) [Streptococcus sanguinis strain CGMH058]
ATGATTGAAGCAATTAAACAATTTGTGGTTTCTGCGGATTTTGTCTTTGCAATCATTATTATTGGCTTCATTGTAGTTGT
TGCCTTGCTTTTATTGGAAAATCGCCGTGATAACCAAAAGCTGGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GTGATTATTCTGAAGTGCTGGACATGCAGGGAAGTCCAGAAATCACGGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACGCATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTTGCGACCAACCGCCGGGGGCAGATTATCACTATCAATGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGAGGGACCTGATTACCAATGTTCCTGAG
CTGACGATAGATTCTCAGGATGAAAATGGTGAGTACTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGACGGGAGTCGGG
CTTTATTTCAGGTTTGGTGGCTGTCCTGCATGATACAACAGAACAAGACAAGGAAGAGCGGGAACGTCGCCTCTTTGTTT
CCAATGTCAGCCATGAGCTGCGGACTCCGTTGACCAGTGTTAAGTCCTATCTGGAAGCCTTAGATGAGGGGGCCCTGTCT
GAGCCAGTAGCACCGGACTTTGTCAAGGTATCGCTCAATGAAACCAACCGCATGATGCGGATGGTGACGGACCTGCTCAG
CTTGTCACGCATTGACAACGAGACCAGTCATCTGGAAGTGGAGCTGACGAATTTTACAGCCTTCATCACCTTTATCCTCA
ATCGCTTTGACAAGATAAAAAATCAAGACGAGACCAAGAAATACGAGATTATCCGTGATTATCCCATTACACCGATTTGG
GTGGAGATTGATACAGATAAGCTGACCCAGGTCATTGATAATATCATGAACAATGCCATCAAGTATTCGCCGGATGGTGG
AACCATTACTGTTTCCATCAAGACAACTGATGAGCAGTTGATTCTTTCGATTGCGGATGAAGGTCTGGGAATTCCCAAGC
AGGACTTGCCTAAGATCTTTGACCGCTTTTATCGAGTGGACAAGGCACGTAGCCGTGCACAGGGCGGAACAGGTCTGGGG
CTGGCTATTGCTAAAGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTGTTACCTTATGAGAATGATGGCGTCCGCGATGACGACTGGGATAATGAAGATGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.773

0.768
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment