Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   GWK28_RS03590 Genome accession   NZ_CP047973
Coordinates   738994..739668 (+) Length   224 a.a.
NCBI ID   WP_004746055.1    Uniprot ID   K7XJ84
Organism   Acinetobacter baumannii strain DETAB-P2     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 733994..744668
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWK28_RS03575 (GWK28_03575) - 734024..735271 (+) 1248 WP_004739776.1 MFS transporter -
  GWK28_RS03580 (GWK28_03580) - 735817..737148 (+) 1332 WP_140982698.1 DcaP family trimeric outer membrane transporter -
  GWK28_RS03585 (GWK28_03585) - 737330..738979 (+) 1650 WP_031946555.1 phosphoethanolamine transferase -
  GWK28_RS03590 (GWK28_03590) ciaR 738994..739668 (+) 675 WP_004746055.1 DNA-binding response regulator PmrA Regulator
  GWK28_RS03595 (GWK28_03595) - 739694..741028 (+) 1335 WP_025469480.1 two-component system sensor histidine kinase PmrB -
  GWK28_RS03600 (GWK28_03600) - 741029..741727 (-) 699 WP_031978550.1 phosphatase PAP2 family protein -
  GWK28_RS03605 (GWK28_03605) - 741880..743067 (-) 1188 WP_002001094.1 ammonium transporter -
  GWK28_RS03610 (GWK28_03610) - 743302..743451 (+) 150 Protein_685 SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25534.40 Da        Isoelectric Point: 5.6117

>NTDB_id=366656 GWK28_RS03590 WP_004746055.1 738994..739668(+) (ciaR) [Acinetobacter baumannii strain DETAB-P2]
MTKILMIEDDFMIAESTTTLLQYHQFEVEWVNNGLDGLAQLAKNKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLQSGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMSHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=366656 GWK28_RS03590 WP_004746055.1 738994..739668(+) (ciaR) [Acinetobacter baumannii strain DETAB-P2]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGACTACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCCCAATTGGCAAAGAATAAGTTTGATCTCATTCTTTTAGATTTGG
GCTTGCCTATGATGGATGGGATGCAGGTTTTAAAGCAAATCCGTCAAAGAGCAGCAACGCCTGTCTTAATTATCTCTGCG
CGTGACCAACTGCAAAACCGTGTTGATGGTTTGAATTTGGGAGCAGATGATTACTTAATTAAGCCATATGAGTTTGATGA
GTTACTTGCTCGCATTCACGCATTATTGCGCCGTAGTGGAGTAGAGGCTCAACTTGCTAGCCAAGATCAACTATTACAAA
GTGGTGATCTGGTTTTAAATGTTGAACAGCATATTGCAACATTTAAAGGGCAACGTATTGATTTATCGAATCGTGAGTGG
GCAATCTTGATTCCGCTTATGAGTCATCCAAATAAAATTTTCTCAAAAGCTAATTTGGAAGATAAGTTATATGACTTTGA
TAGTGATGTGACCAGCAACACGATTGAGGTATATGTCCATCATTTAAGGGCTAAGTTGGGTAAAGACTTTATTCGAACTA
TCCGAGGACTGGGTTACCGTTTAGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K7XJ84

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

36.842

100

0.375