Detailed information NTG0036573

Bioinformatically predicted

Overview

• Name: comB
• Type: Regulator
• Locus tag: SMUNN2025_RS01335
• Genome accession: NC_013928
• Coordinates: 272352..273365 (-)
• Length: 337 a.a.
• NCBI ID: WP_002278097.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 267352..278365

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS01310 (SmuNN2025_0241)	-	267836..268240 (+)	405	WP_002263912.1	hypothetical protein	-
SMUNN2025_RS10600	-	268363..268575 (-)	213	Protein_237	IS3 family transposase	-
SMUNN2025_RS10505	-	269015..269179 (+)	165	WP_002265308.1	hypothetical protein	-
SMUNN2025_RS01320 (SmuNN2025_0245)	-	269584..269796 (+)	213	WP_002264173.1	Blp family class II bacteriocin	-
SMUNN2025_RS01325 (SmuNN2025_0246)	-	269960..270148 (+)	189	WP_002270918.1	Blp family class II bacteriocin	-
SMUNN2025_RS01330 (SmuNN2025_0247)	-	270634..271656 (+)	1023	WP_002278096.1	thioredoxin family protein	-
SMUNN2025_RS10510 (SmuNN2025_0248)	-	271947..272090 (+)	144	WP_002263740.1	hypothetical protein	-
SMUNN2025_RS01335 (SmuNN2025_0249)	comB	272352..273365 (-)	1014	WP_002278097.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
SMUNN2025_RS01340 (SmuNN2025_0250)	-	273378..275592 (-)	2215	Protein_244	peptide cleavage/export ABC transporter	-
SMUNN2025_RS01350 (SmuNN2025_0252)	-	275981..276145 (+)	165	WP_002271839.1	Blp family class II bacteriocin	-
SMUNN2025_RS01355 (SmuNN2025_0253)	-	276283..276468 (+)	186	WP_002263346.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SMUNN2025_RS01360 (SmuNN2025_0254)	-	276769..276963 (+)	195	WP_148211844.1	Blp family class II bacteriocin	-
SMUNN2025_RS01365 (SmuNN2025_0255)	-	277003..277167 (+)	165	WP_024784658.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
SMUNN2025_RS01370 (SmuNN2025_0256)	-	277622..277885 (+)	264	WP_002352361.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 337 a.a.
• Molecular weight: 38417.10 Da
• Isoelectric Point: 10.7718

>NTDB_id=36573 SMUNN2025_RS01335 WP_002278097.1 272352..273365(-) (comB) [Streptococcus mutans NN2025]
MNPNLFKSAEFYRRRYHNFATVLIIPLVCLLVFLFIFLLFAKKEVTVLSDGEISPIKVIDVIQSKSDYPISENNLTDNHA
VKKGDVLIQYVNPAANTRQGGNNQNQNQSQNKQNKNQQQNNKNQKNGNQGQKNQNQNQNKKDQKNNNQSQQNKQGQKKTN
QSQNQQNKNQNKNQSQNKQNGNQNQNNWNQNNQNDKVTASQDGVIHTNPKYEGENLIPRGTKIAQLYPDINKTRQVLITY
YVSSKDVTRLKQGQKTRLALTKVGNDQISIRGKINSIASAATTTKKGNVFKVTAKAKVSKKDSQTIKYGLQGKTITVVEK
KTFFDYYKDKLLNKNQK

Nucleotide

• Length: 1014 bp

>NTDB_id=36573 SMUNN2025_RS01335 WP_002278097.1 272352..273365(-) (comB) [Streptococcus mutans NN2025]
ATGAACCCAAATTTATTTAAAAGCGCTGAATTCTACCGAAGACGCTATCATAATTTTGCTACAGTTCTTATTATTCCTTT
GGTTTGTTTACTTGTATTTTTATTTATCTTTCTATTATTTGCTAAAAAAGAGGTCACTGTCTTGTCTGATGGCGAGATCT
CTCCCATTAAAGTAATTGATGTTATTCAATCTAAAAGTGATTATCCCATTTCTGAAAATAATTTAACAGATAATCACGCC
GTTAAAAAAGGGGATGTTCTCATCCAATATGTTAATCCAGCAGCAAATACAAGACAGGGCGGAAATAATCAGAATCAAAA
TCAATCTCAAAACAAGCAAAATAAGAATCAGCAGCAAAACAATAAGAATCAAAAAAACGGCAATCAAGGTCAAAAAAATC
AAAATCAGAACCAAAATAAAAAGGATCAGAAAAACAATAACCAATCTCAGCAAAACAAGCAAGGACAAAAGAAAACTAAT
CAATCCCAAAATCAGCAGAATAAGAATCAAAATAAAAACCAATCTCAAAACAAACAAAATGGGAATCAAAACCAAAATAA
CTGGAATCAGAATAATCAAAATGATAAAGTCACAGCCAGCCAAGATGGTGTTATCCATACCAACCCCAAATATGAAGGTG
AAAACTTAATTCCTCGGGGGACTAAAATCGCACAGCTCTATCCAGATATTAACAAAACAAGACAAGTTCTGATCACTTAT
TACGTCTCCTCTAAAGATGTCACCCGCCTCAAACAAGGCCAAAAGACTCGTCTTGCTTTAACCAAGGTAGGAAATGATCA
AATTTCCATTAGAGGAAAAATTAATAGTATCGCTTCAGCTGCTACAACGACGAAAAAAGGCAATGTTTTTAAAGTGACAG
CTAAAGCAAAAGTTTCTAAAAAAGACAGCCAAACCATTAAATACGGCCTCCAGGGTAAAACCATCACAGTTGTTGAAAAA
AAGACTTTCTTTGATTATTATAAAGATAAACTGTTAAATAAAAATCAAAAATAA

Domains

Predicted by InterproScan.

• HlyD family secretion protein (HlyD_3) (196-309)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB	Streptococcus mutans UA159	99.11	100	0.991