Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   SMUNN2025_RS01500 Genome accession   NC_013928
Coordinates   305761..306447 (-) Length   228 a.a.
NCBI ID   WP_002278087.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 300761..311447
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS01470 (SmuNN2025_0277) - 302735..302938 (-) 204 WP_002267523.1 hypothetical protein -
  SMUNN2025_RS01475 (SmuNN2025_0278) - 303243..303488 (+) 246 WP_002263367.1 hypothetical protein -
  SMUNN2025_RS01480 (SmuNN2025_0279) rpsF 303644..303934 (+) 291 WP_002261866.1 30S ribosomal protein S6 -
  SMUNN2025_RS01485 (SmuNN2025_0280) ssbA 303952..304446 (+) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  SMUNN2025_RS01490 (SmuNN2025_0281) rpsR 304476..304715 (+) 240 WP_000068664.1 30S ribosomal protein S18 -
  SMUNN2025_RS01495 (SmuNN2025_0282) - 305034..305753 (+) 720 WP_041160309.1 TraX family protein -
  SMUNN2025_RS01500 (SmuNN2025_0283) hdrM 305761..306447 (-) 687 WP_002278087.1 hdrR negative regulator HdrM Regulator
  SMUNN2025_RS01505 (SmuNN2025_0284) hdrR 306444..306800 (-) 357 WP_002262669.1 LytTR family transcriptional regulator HdrR Regulator
  SMUNN2025_RS01510 (SmuNN2025_0285) - 306939..307601 (-) 663 WP_002278088.1 DUF1129 domain-containing protein -
  SMUNN2025_RS01515 (SmuNN2025_0286) - 307755..308699 (-) 945 WP_002262667.1 magnesium transporter CorA family protein -
  SMUNN2025_RS01520 - 309099..309320 (-) 222 WP_019312622.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26179.20 Da        Isoelectric Point: 6.4881

>NTDB_id=36576 SMUNN2025_RS01500 WP_002278087.1 305761..306447(-) (hdrM) [Streptococcus mutans NN2025]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFFKPHYSYSYKGNHYFNMKQNANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDLSQAQ
FMTDSPEIHIDVSFGETNLRIPNNWKIINKTHSPFASISFSDFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=36576 SMUNN2025_RS01500 WP_002278087.1 305761..306447(-) (hdrM) [Streptococcus mutans NN2025]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCCCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATTTTAAATAGTTTCTTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAAAATGCTAACTATATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATCTCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATGTTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCCCCCTTTGCTTCCATTTCATTTTCAGATTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

98.684

100

0.987

Multiple sequence alignment