Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SMUNN2025_RS01245 Genome accession   NC_013928
Coordinates   255721..256413 (+) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 250721..261413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS01225 (SmuNN2025_0223) - 250832..253444 (-) 2613 WP_012997564.1 ABC transporter permease -
  SMUNN2025_RS01230 (SmuNN2025_0224) - 253446..254153 (-) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  SMUNN2025_RS01235 (SmuNN2025_0225) - 254261..254836 (+) 576 WP_002274867.1 TetR/AcrR family transcriptional regulator -
  SMUNN2025_RS01240 (SmuNN2025_0226) - 254829..255365 (+) 537 WP_002262122.1 DUF177 domain-containing protein -
  SMUNN2025_RS01245 (SmuNN2025_0227) covR 255721..256413 (+) 693 WP_002262121.1 response regulator GcrR Regulator
  SMUNN2025_RS01250 (SmuNN2025_0228) nrdR 256783..257274 (+) 492 WP_002262120.1 transcriptional regulator NrdR -
  SMUNN2025_RS01255 (SmuNN2025_0229) - 257261..258430 (+) 1170 WP_002262119.1 DnaD domain protein -
  SMUNN2025_RS01260 (SmuNN2025_0230) dnaI 258431..259330 (+) 900 WP_002265120.1 primosomal protein DnaI -
  SMUNN2025_RS01265 (SmuNN2025_0231) der 259343..260653 (+) 1311 WP_002277684.1 ribosome biogenesis GTPase Der -
  SMUNN2025_RS01270 (SmuNN2025_0232) - 260728..261354 (+) 627 WP_002277685.1 hypothetical protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=36568 SMUNN2025_RS01245 WP_002262121.1 255721..256413(+) (covR) [Streptococcus mutans NN2025]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=36568 SMUNN2025_RS01245 WP_002262121.1 255721..256413(+) (covR) [Streptococcus mutans NN2025]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGTCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment