Detailed information NTG0364577

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FDY98_RS10935
• Genome accession: NZ_CP040451
• Coordinates: 2380155..2381000 (-)
• Length: 281 a.a.
• NCBI ID: WP_027959304.1
• Uniprot ID: A0A6B8QQH4
• Organism: Halomonas sp. PA16-9
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2375155..2386000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FDY98_RS10905 (FDY98_10960)	-	2376244..2376617 (+)	374	Protein_2340	histone-like nucleoid-structuring protein, MvaT/MvaU family	-
FDY98_RS27790	-	2377221..2377352 (-)	132	WP_340146484.1	helix-turn-helix domain-containing protein	-
FDY98_RS10915 (FDY98_10970)	-	2377907..2378266 (+)	360	WP_035537408.1	hypothetical protein	-
FDY98_RS10920 (FDY98_10975)	-	2378290..2379177 (-)	888	WP_022523596.1	hypothetical protein	-
FDY98_RS10925 (FDY98_10980)	yacG	2379217..2379450 (-)	234	WP_022523595.1	DNA gyrase inhibitor YacG	-
FDY98_RS10930 (FDY98_10985)	coaE	2379486..2380075 (-)	590	Protein_2345	dephospho-CoA kinase	-
FDY98_RS10935 (FDY98_10990)	pilD	2380155..2381000 (-)	846	WP_027959304.1	A24 family peptidase	Machinery gene
FDY98_RS10940 (FDY98_11000)	pilC	2381193..2382425 (-)	1233	WP_027959305.1	type II secretion system F family protein	Machinery gene
FDY98_RS10945 (FDY98_11005)	pilB	2382429..2384177 (-)	1749	WP_027959306.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FDY98_RS10950 (FDY98_11010)	-	2384419..2384919 (+)	501	WP_196517982.1	pilin	-
FDY98_RS10955 (FDY98_11015)	-	2385032..2385466 (+)	435	WP_027959308.1	anti-virulence regulator CigR family protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 30801.12 Da
• Isoelectric Point: 7.2769

>NTDB_id=364577 FDY98_RS10935 WP_027959304.1 2380155..2381000(-) (pilD) [Halomonas sp. PA16-9]
MHHPPFILWLIVLLIGLCLGSFLNVVITRLPVMLMRGWRNEAREALELSAEHSPRFNLVTPGSMCPRCEAPIAWHDNLPL
IGWIKRRGRCAECQTPISVQYPLVEVAGGLLAMAVLALHGLTAESAFVYGACLMLLVLAVIDFRTQLLPDIITLPLLWAG
LLFQLLFQPLMLPSAVIGAMVGYLSLWSFYWLFKLATGKEGMGYGDFKLLAALGAWLGWSFLPLILILSAGLGAIVGLVA
QAYSPNLRGTPFPFGPFLALAGWVALLVGDEIMAMYLNLLM

Nucleotide

• Length: 846 bp

>NTDB_id=364577 FDY98_RS10935 WP_027959304.1 2380155..2381000(-) (pilD) [Halomonas sp. PA16-9]
ATGCATCACCCTCCGTTTATCCTGTGGTTAATCGTTTTATTGATTGGGCTATGCCTGGGCAGTTTTCTAAATGTGGTGAT
TACGCGCCTGCCGGTGATGCTGATGCGTGGCTGGCGTAATGAAGCCCGCGAAGCACTTGAGCTTAGCGCTGAACACTCAC
CACGTTTTAATTTGGTCACACCAGGCTCTATGTGTCCACGCTGTGAAGCCCCCATTGCATGGCACGACAACCTGCCACTG
ATTGGCTGGATAAAGCGCCGCGGCCGCTGCGCTGAGTGCCAAACGCCGATTAGCGTTCAATATCCTCTGGTAGAAGTAGC
CGGTGGCTTACTGGCCATGGCGGTGCTAGCGCTCCACGGGCTTACGGCAGAATCAGCCTTCGTCTACGGGGCCTGCCTGA
TGCTGTTAGTGCTCGCCGTGATCGACTTTCGCACCCAGCTTCTCCCCGACATCATCACCCTCCCCTTGCTTTGGGCAGGG
TTACTGTTTCAGCTCCTCTTCCAGCCACTGATGCTGCCAAGTGCCGTTATCGGCGCAATGGTAGGCTATCTTTCACTGTG
GAGCTTTTATTGGCTATTCAAACTGGCCACCGGCAAAGAGGGTATGGGCTATGGCGACTTTAAGCTGCTGGCAGCACTAG
GCGCCTGGCTGGGTTGGAGTTTTTTACCGCTAATATTGATACTTTCCGCAGGGCTTGGGGCCATTGTTGGGCTAGTTGCC
CAGGCCTACTCACCTAACCTACGCGGCACACCGTTTCCCTTCGGCCCTTTTCTCGCCCTCGCCGGCTGGGTGGCGTTGTT
AGTCGGTGATGAAATAATGGCAATGTATCTCAACCTGCTTATGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (132-238)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (14-116)

3D structure

• AlphaFold DB: A0A6B8QQH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	49.286	99.644	0.491
pilD	Acinetobacter baumannii D1279779	47.273	97.865	0.463
pilD	Acinetobacter nosocomialis M2	47.273	97.865	0.463
pilD	Vibrio campbellii strain DS40M4	42.958	100	0.434
pilD	Neisseria gonorrhoeae MS11	45.211	92.883	0.42