Detailed information NTG0362634

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: FD735_RS02310
• Genome accession: NZ_CP040231
• Coordinates: 398401..399060 (-)
• Length: 219 a.a.
• NCBI ID: WP_139658379.1
• Uniprot ID: A0A5B7Y4P6
• Organism: Streptococcus sp. 1643
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 393401..404060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD735_RS02280 (FD735_02280)	-	393528..394094 (+)	567	WP_139658378.1	aminodeoxychorismate/anthranilate synthase component II	-
FD735_RS02285 (FD735_02285)	trpD	394105..395109 (+)	1005	WP_042902637.1	anthranilate phosphoribosyltransferase	-
FD735_RS02290 (FD735_02290)	trpC	395106..395873 (+)	768	WP_042902638.1	indole-3-glycerol phosphate synthase TrpC	-
FD735_RS02295 (FD735_02295)	-	395860..396459 (+)	600	WP_042902639.1	phosphoribosylanthranilate isomerase	-
FD735_RS02300 (FD735_02300)	trpB	396437..397660 (+)	1224	WP_042902640.1	tryptophan synthase subunit beta	-
FD735_RS02305 (FD735_02305)	trpA	397653..398429 (+)	777	WP_042902641.1	tryptophan synthase subunit alpha	-
FD735_RS02310 (FD735_02310)	cclA/cilC	398401..399060 (-)	660	WP_139658379.1	A24 family peptidase	Machinery gene
FD735_RS02315 (FD735_02315)	-	399130..399585 (+)	456	WP_139658380.1	GNAT family N-acetyltransferase	-
FD735_RS02320 (FD735_02320)	-	399689..400213 (+)	525	WP_139658381.1	thiol-disulfide isomerase	-
FD735_RS02325 (FD735_02325)	-	400356..400805 (+)	450	WP_139658382.1	hypothetical protein	-
FD735_RS02330 (FD735_02330)	-	401024..401227 (-)	204	WP_000102421.1	CsbD family protein	-
FD735_RS02335 (FD735_02335)	-	401269..401853 (-)	585	WP_000072931.1	Asp23/Gls24 family envelope stress response protein	-
FD735_RS02340 (FD735_02340)	-	401865..402035 (-)	171	WP_000454669.1	DUF2273 domain-containing protein	-
FD735_RS02345 (FD735_02345)	amaP	402046..402609 (-)	564	WP_139658383.1	alkaline shock response membrane anchor protein AmaP	-
FD735_RS02350 (FD735_02350)	-	402709..402945 (-)	237	WP_000964741.1	GlsB/YeaQ/YmgE family stress response membrane protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 25026.23 Da
• Isoelectric Point: 8.8126

>NTDB_id=362634 FD735_RS02310 WP_139658379.1 398401..399060(-) (cclA/cilC) [Streptococcus sp. 1643]
MIDLYFFLVGSILASFLGLVIDRFPEQSIIRPASHCDSCQTRLRPSDLIPILSQVFNRFRCRYCKIRYPFWYALFEFGLG
LIFLTWSWGFLSLGQVVLITAGLTLGIYDFRHQEYPLLVWLTFHLILMACSGWNLVMIFFLVLGIMAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFSSAAGILAFLSQKKKKRLPFVPFLLLATCVIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=362634 FD735_RS02310 WP_139658379.1 398401..399060(-) (cclA/cilC) [Streptococcus sp. 1643]
ATGATTGATCTTTATTTTTTTCTTGTTGGGAGCATTCTCGCTTCCTTTCTAGGTTTGGTCATTGACCGTTTTCCTGAGCA
ATCCATTATTCGACCGGCTAGTCACTGTGATTCCTGTCAGACTCGCTTGCGTCCCTCAGATTTGATTCCTATTCTCTCGC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAGATTCGCTATCCATTCTGGTATGCCCTTTTTGAATTCGGCTTAGGA
CTCATCTTTCTGACTTGGTCTTGGGGCTTTCTTTCCTTGGGGCAAGTCGTCCTTATCACTGCTGGTTTGACCTTGGGCAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTAGTCTGGCTGACGTTCCACCTAATCCTCATGGCCTGCTCTGGCTGGA
ATCTGGTTATGATTTTCTTCCTTGTCCTCGGAATCATGGCCCATTTTATCGATATCCGCATGGGAGCAGGAGATTTTCTA
TTTCTGGCTTCTTGTGCGCTCGTTTTTAGTGTGACAGAATTACTCATCTTGATTCAGTTCTCTTCGGCAGCAGGGATTTT
AGCCTTTCTTTCGCAAAAGAAAAAGAAAAGACTTCCTTTTGTACCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A5B7Y4P6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	89.498	100	0.895
cclA/cilC	Streptococcus pneumoniae TIGR4	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae Rx1	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae D39	87.671	100	0.877
cclA/cilC	Streptococcus pneumoniae R6	87.671	100	0.877
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863