Detailed information NTG0358844

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: E8M06_RS04510
• Genome accession: NZ_CP039462
• Coordinates: 903823..905202 (+)
• Length: 459 a.a.
• NCBI ID: WP_136581250.1
• Uniprot ID: -
• Organism: Streptococcus suis strain WUSS351
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 898823..910202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E8M06_RS04480 (E8M06_04485)	pstA	899156..900043 (+)	888	WP_014635996.1	phosphate ABC transporter permease PstA	-
E8M06_RS04485 (E8M06_04490)	pstB	900068..900871 (+)	804	WP_024413123.1	phosphate ABC transporter ATP-binding protein PstB	-
E8M06_RS04490 (E8M06_04495)	pstB	900883..901641 (+)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
E8M06_RS04495 (E8M06_04500)	phoU	901670..902326 (+)	657	WP_136581248.1	phosphate signaling complex protein PhoU	-
E8M06_RS04500 (E8M06_04505)	-	902492..902965 (+)	474	WP_136581249.1	hypothetical protein	-
E8M06_RS04505 (E8M06_04510)	ciaR	903159..903830 (+)	672	WP_014637852.1	response regulator transcription factor	Regulator
E8M06_RS04510 (E8M06_04515)	ciaH	903823..905202 (+)	1380	WP_136581250.1	HAMP domain-containing sensor histidine kinase	Regulator
E8M06_RS04515 (E8M06_04520)	-	905303..906532 (+)	1230	WP_044679497.1	transglutaminase domain-containing protein	-
E8M06_RS04520 (E8M06_04525)	rpsT	906795..907043 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
E8M06_RS04525 (E8M06_04530)	coaA	907102..908022 (-)	921	WP_002935283.1	type I pantothenate kinase	-
E8M06_RS04530 (E8M06_04535)	-	908131..908721 (+)	591	WP_024376492.1	class I SAM-dependent methyltransferase	-
E8M06_RS04535 (E8M06_04540)	-	908718..909995 (+)	1278	WP_024385288.1	pyrimidine-nucleoside phosphorylase	-

Sequence

Protein

• Length: 459 a.a.
• Molecular weight: 51828.35 Da
• Isoelectric Point: 5.8702

>NTDB_id=358844 E8M06_RS04510 WP_136581250.1 903823..905202(+) (ciaH) [Streptococcus suis strain WUSS351]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSTPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELPTDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide

• Length: 1380 bp

>NTDB_id=358844 E8M06_RS04510 WP_136581250.1 903823..905202(+) (ciaH) [Streptococcus suis strain WUSS351]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCCGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCACGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
TGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGCCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCTAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTATTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTTATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTCTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACATTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (350-458)

• His Kinase A (phospho-acceptor) domain (HisKA) (240-306)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus pneumoniae Rx1	49.353	100	0.499
ciaH	Streptococcus pneumoniae D39	49.353	100	0.499
ciaH	Streptococcus pneumoniae R6	49.353	100	0.499
ciaH	Streptococcus pneumoniae TIGR4	49.353	100	0.499
ciaH	Streptococcus mutans UA159	50.336	97.386	0.49