Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   E8M06_RS03740 Genome accession   NZ_CP039462
Coordinates   751561..753798 (+) Length   745 a.a.
NCBI ID   WP_136581209.1    Uniprot ID   -
Organism   Streptococcus suis strain WUSS351     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 746561..758798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS03715 (E8M06_03715) - 746632..747561 (-) 930 WP_136581207.1 ABC transporter substrate-binding protein -
  E8M06_RS03720 (E8M06_03720) - 747574..748359 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  E8M06_RS03725 (E8M06_03725) - 748511..749956 (-) 1446 WP_136581208.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  E8M06_RS03730 (E8M06_03730) - 750102..750848 (+) 747 WP_105112803.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  E8M06_RS03735 (E8M06_03735) - 750915..751577 (+) 663 WP_105112804.1 helix-hairpin-helix domain-containing protein -
  E8M06_RS03740 (E8M06_03740) comEC/celB 751561..753798 (+) 2238 WP_136581209.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84045.84 Da        Isoelectric Point: 6.6711

>NTDB_id=358842 E8M06_RS03740 WP_136581209.1 751561..753798(+) (comEC/celB) [Streptococcus suis strain WUSS351]
MSRLSKLPCQPIHLAVLAVAVYFAVHSFSLLTMGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGCQKVQWERADQSA
PEQVTTVQVIPDTIEVSGDSLSFRGWADGQTYQVFYKLASQEEQTYFQELTDLVQLDVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPILMTYFYAFQPLSILLTFVFSFIFDVLLLPGLSV
IFLLSPIIKITWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSQGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWKEWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=358842 E8M06_RS03740 WP_136581209.1 751561..753798(+) (comEC/celB) [Streptococcus suis strain WUSS351]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCATTCACCTGGCAGTATTGGCGGTGGCAGTTTACTTTGCAGTCCATTC
TTTTTCCCTCTTGACAATGGGCCTGCTGAGTTTGTTGTTGCTGGTCTTTGGATTTCGACAAGGCAAGGCAGTGTTCATCA
AAACGCTGCCGCTTTTAGCCCTATGTGGTCTGTTTTTCGGATGCCAAAAGGTTCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTGCAGGTCATTCCAGATACCATTGAAGTCAGCGGGGACAGCCTGTCCTTTCGTGGTTGGGC
TGACGGACAAACCTATCAGGTGTTTTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGACTGATCTGG
TCCAGCTAGATGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGACTATCAGGCCTATCTG
AAAACACAGGGTATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTCGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGATTCTCATGACCTATTTCTATG
CCTTCCAGCCCTTGTCTATTCTCTTGACTTTTGTCTTTTCCTTTATCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGCTTTCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTCGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACGCACACCGATACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCAGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGATCGCTTGCCAATTTTTGACT
CCTATCTGGAAGTCCTCTATCCAGATGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAGGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGATCCAAAGGTTCTTCCTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCTC
TGGTATCTGCTGGAGAAAATAACCGCTACAAGCACCCTCACCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGGGCAATCCGCTTCCGAGGCTGGAAGGAGTGGAGGATTGAAACGGTGAGGGAGTAG

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(28-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)

Competence protein (Competence)

(215-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.24

99.732

0.541
  comEC/celB Streptococcus mitis NCTC 12261

53.306

99.463

0.53
  comEC/celB Streptococcus pneumoniae TIGR4

52.426

99.597

0.522
  comEC/celB Streptococcus pneumoniae Rx1

52.156

99.597

0.519
  comEC/celB Streptococcus pneumoniae D39

52.156

99.597

0.519
  comEC/celB Streptococcus pneumoniae R6

52.156

99.597

0.519
  comEC Lactococcus lactis subsp. cremoris KW2

48.525

100

0.486

Multiple sequence alignment