Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   E8M06_RS02375 Genome accession   NZ_CP039462
Coordinates   476371..477663 (+) Length   430 a.a.
NCBI ID   WP_136581113.1    Uniprot ID   -
Organism   Streptococcus suis strain WUSS351     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 471371..482663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M06_RS02350 (E8M06_02350) - 472177..472818 (+) 642 WP_002937025.1 response regulator transcription factor -
  E8M06_RS02355 (E8M06_02355) - 472868..474268 (+) 1401 WP_014637530.1 Cof-type HAD-IIB family hydrolase -
  E8M06_RS02360 (E8M06_02360) - 474270..474641 (+) 372 WP_136581112.1 S1 RNA-binding domain-containing protein -
  E8M06_RS02365 (E8M06_02365) cysK 474667..475592 (-) 926 Protein_425 cysteine synthase A -
  E8M06_RS02370 (E8M06_02370) - 475682..476314 (-) 633 WP_015646510.1 YigZ family protein -
  E8M06_RS02375 (E8M06_02375) comFA/cflA 476371..477663 (+) 1293 WP_136581113.1 DEAD/DEAH box helicase Machinery gene
  E8M06_RS02380 (E8M06_02380) comFC/cflB 477656..478321 (+) 666 WP_105156084.1 ComF family protein Machinery gene
  E8M06_RS02385 (E8M06_02385) raiA 478398..478940 (+) 543 WP_004194117.1 ribosome-associated translation inhibitor RaiA -
  E8M06_RS02390 (E8M06_02390) - 479016..480272 (-) 1257 WP_105179941.1 ISL3 family transposase -
  E8M06_RS11350 (E8M06_02395) - 480320..480634 (+) 315 WP_136581114.1 hypothetical protein -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48973.54 Da        Isoelectric Point: 9.0359

>NTDB_id=358839 E8M06_RS02375 WP_136581113.1 476371..477663(+) (comFA/cflA) [Streptococcus suis strain WUSS351]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKMNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLNRLSLPRRFHGNPLVVPQKVWFSRFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=358839 E8M06_RS02375 WP_136581113.1 476371..477663(+) (comFA/cflA) [Streptococcus suis strain WUSS351]
ATGAAAGAATTAGAAAATTATTACGGTAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAATGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAACCGTCTTAGTTTGCCAAGGCGATTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAGATTCGATGATACCCTAAAGAAAAATAGACTAGTCCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATCGTTGAGGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTAACCTTCCCATGTGTAGATGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGCAGAAGTATGGAACGTCCGACTGGG
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

53.186

94.884

0.505
  comFA Latilactobacillus sakei subsp. sakei 23K

37.674

100

0.377
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363

Multiple sequence alignment