Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   E8M05_RS09125 Genome accession   NZ_CP039457
Coordinates   1744681..1745373 (-) Length   230 a.a.
NCBI ID   WP_003066186.1    Uniprot ID   A0AAW6YHD4
Organism   Streptococcus pasteurianus strain WUSP067     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1739681..1750373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS09105 (E8M05_09095) dnaI 1740456..1741358 (-) 903 WP_013852182.1 primosomal protein DnaI -
  E8M05_RS09110 (E8M05_09100) - 1741369..1742526 (-) 1158 WP_003066180.1 DnaD domain protein -
  E8M05_RS09115 (E8M05_09105) nrdR 1742513..1743007 (-) 495 WP_003066183.1 transcriptional regulator NrdR -
  E8M05_RS09120 (E8M05_09110) - 1743197..1744681 (-) 1485 WP_003066184.1 ATP-binding protein -
  E8M05_RS09125 (E8M05_09115) covR 1744681..1745373 (-) 693 WP_003066186.1 response regulator transcription factor Regulator
  E8M05_RS09130 (E8M05_09120) - 1745618..1746154 (-) 537 WP_013852190.1 DUF177 domain-containing protein -
  E8M05_RS09135 (E8M05_09125) htpX 1746293..1747192 (-) 900 WP_003066190.1 zinc metalloprotease HtpX -
  E8M05_RS09140 (E8M05_09130) - 1747319..1747867 (-) 549 WP_013852188.1 LemA family protein -
  E8M05_RS09145 (E8M05_09135) rsmG 1748198..1748911 (+) 714 WP_041973360.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  E8M05_RS09150 (E8M05_09140) - 1748981..1750354 (+) 1374 WP_003066196.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26543.50 Da        Isoelectric Point: 4.7752

>NTDB_id=358804 E8M05_RS09125 WP_003066186.1 1744681..1745373(-) (covR) [Streptococcus pasteurianus strain WUSP067]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVEFKREQGNQGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLANVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=358804 E8M05_RS09125 WP_003066186.1 1744681..1745373(-) (covR) [Streptococcus pasteurianus strain WUSP067]
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGCTTTGTGTCTTTGGAATTACAACATGAAGGTTA
TTCAGTAGTTGTAGAAACAAACGGGCGTTTAGGGCTTCAAACAGCTCTTGATGATGATTTTGACTTGATTTTGCTTGATT
TAATGCTTCCAGATATGGATGGATTTGAAATTACGCGTCGTCTTCGATTGGAAAAAGAAACTTCTATTATTATGATGACA
GCTCGCGACTCTATTATGGATATTGTTGCTGGGCTTGATCGTGGTGCAGACGACTATATTGTCAAACCATTTGCAATTGA
AGAACTCTTGGCTCGTGTTCGTGCCGTTTTTCGTCGGCAAGATGTTGAATTTAAACGAGAACAGGGTAATCAAGGAAAAG
AAGGATTGCTTGGTCTACGCTTAAATCCTCAAAATCGTTCAGCGGTTCGAGGTGATGATGAAATTTCGCTTACAAAACGT
GAGTACGATTTGTTAAGTGTTCTTTTGTCGAATGTTAATCGTGTAATGACACGTGAAGAACTGTTAGCCAATGTTTGGAG
ATATGATACTGATATTGAGACAAATGTTGTTGATGTTTACATTCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGCTACATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

99.565

0.635
  vicR Streptococcus mutans UA159

41.991

100

0.422
  micA Streptococcus pneumoniae Cp1015

41.304

100

0.413

Multiple sequence alignment