Detailed information NTG0358044

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: E4T61_RS16910
• Genome accession: NZ_CP039297
• Coordinates: 3414434..3415597 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis isolate UFLA258
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3409434..3420597

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E4T61_RS16880 (E4T61_16880)	-	3409698..3410117 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
E4T61_RS16885 (E4T61_16885)	comFC	3410191..3410880 (-)	690	WP_219152091.1	phosphoribosyltransferase family protein	Machinery gene
E4T61_RS16890 (E4T61_16890)	-	3410886..3411170 (-)	285	WP_007407481.1	competence protein ComFB	-
E4T61_RS16895 (E4T61_16895)	comFA	3411228..3412613 (-)	1386	WP_136396658.1	DEAD/DEAH box helicase	Machinery gene
E4T61_RS16900 (E4T61_16900)	-	3412722..3413570 (-)	849	WP_136396659.1	DegV family protein	-
E4T61_RS16905 (E4T61_16905)	degU	3413668..3414357 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
E4T61_RS16910 (E4T61_16910)	degS	3414434..3415597 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
E4T61_RS16915 (E4T61_16915)	-	3415820..3416467 (+)	648	WP_136396660.1	YigZ family protein	-
E4T61_RS16920 (E4T61_16920)	-	3416472..3417692 (+)	1221	WP_012118574.1	LCP family protein	-
E4T61_RS16925 (E4T61_16925)	-	3417792..3418868 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
E4T61_RS16930 (E4T61_16930)	-	3419001..3420197 (-)	1197	WP_136396661.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=358044 E4T61_RS16910 WP_007407484.1 3414434..3415597(-) (degS) [Bacillus velezensis isolate UFLA258]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=358044 E4T61_RS16910 WP_007407484.1 3414434..3415597(-) (degS) [Bacillus velezensis isolate UFLA258]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGACCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951