Detailed information NTG0357728

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: E6P07_RS02720
• Genome accession: NZ_CP039268
• Coordinates: 580369..581259 (-)
• Length: 296 a.a.
• NCBI ID: WP_153974190.1
• Uniprot ID: A0A6I6DWW0
• Organism: Thermochromatium tepidum ATCC 43061
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 575369..586259

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E6P07_RS02695 (E6P07_02695)	ruvC	576123..576659 (+)	537	WP_153974185.1	crossover junction endodeoxyribonuclease RuvC	-
E6P07_RS02700 (E6P07_02700)	ruvA	576663..577289 (+)	627	WP_153974186.1	Holliday junction branch migration protein RuvA	-
E6P07_RS02705 (E6P07_02705)	-	577394..579064 (+)	1671	WP_153974187.1	sensor domain-containing diguanylate cyclase	-
E6P07_RS02710 (E6P07_02710)	-	579285..579629 (-)	345	WP_153974188.1	hypothetical protein	-
E6P07_RS02715 (E6P07_02715)	coaE	579746..580372 (-)	627	WP_153974189.1	dephospho-CoA kinase	-
E6P07_RS02720 (E6P07_02720)	pilD	580369..581259 (-)	891	WP_153974190.1	A24 family peptidase	Machinery gene
E6P07_RS02725 (E6P07_02725)	pilC	581285..582535 (-)	1251	WP_153974191.1	type II secretion system F family protein	Machinery gene
E6P07_RS02730 (E6P07_02730)	pilB	582556..584271 (-)	1716	WP_153974192.1	type IV-A pilus assembly ATPase PilB	Machinery gene
E6P07_RS02735 (E6P07_02735)	-	584297..585130 (-)	834	WP_211363158.1	NYN domain-containing protein	-

Sequence

Protein

• Length: 296 a.a.
• Molecular weight: 31594.51 Da
• Isoelectric Point: 6.4686

>NTDB_id=357728 E6P07_RS02720 WP_153974190.1 580369..581259(-) (pilD) [Thermochromatium tepidum ATCC 43061]
MSVPVWLEPLETNPCLLSTSAVLLGLVLGSFLNVVILRLPRMLEASWRRDCAELLGSDAPAPETDAPPLSLSQPASTCPA
CGHRIRAHENIPILSYLLLRGRCSACKNRISPRYPLIEGLTALLTLIVVIHFGLTVQTAAALVLTWSLIALAVIDLDTQL
LPDAITLPLIWIGLALSLFGVFALPEEAIVGAIAGYLSLWVVFQLFRLATGKEGLGYGDFKLLALLGAWLGWTALPQIIL
LSALVGALVGIGLILSGRHASDKPLPFGPYLAAAGWISLIWGESINNAYLRLSGLG

Nucleotide

• Length: 891 bp

>NTDB_id=357728 E6P07_RS02720 WP_153974190.1 580369..581259(-) (pilD) [Thermochromatium tepidum ATCC 43061]
ATGTCGGTGCCCGTCTGGCTGGAGCCGCTCGAGACGAACCCCTGCCTGCTCTCTACGAGCGCCGTGCTGCTTGGGCTCGT
CCTCGGCAGCTTCCTCAATGTCGTCATCCTGCGTCTGCCGCGCATGCTGGAGGCCAGCTGGCGACGCGATTGCGCCGAAC
TCCTGGGTTCCGACGCACCGGCACCCGAGACCGATGCCCCGCCGCTCAGTCTGTCGCAACCGGCCTCGACCTGTCCGGCC
TGTGGGCATCGGATCCGCGCCCACGAGAACATCCCGATCCTCAGCTATCTGCTGCTGCGTGGACGTTGCTCGGCCTGCAA
GAACAGGATCAGCCCGCGCTACCCACTCATCGAGGGTCTCACGGCGCTCCTGACCCTGATCGTGGTGATCCATTTCGGTC
TGACGGTGCAGACAGCGGCCGCCCTGGTCCTGACCTGGTCGCTGATCGCGCTCGCCGTCATCGATCTCGATACCCAACTC
TTGCCGGATGCCATTACCCTGCCCCTCATCTGGATCGGGCTCGCTTTAAGCCTGTTCGGGGTCTTTGCCCTGCCCGAGGA
GGCCATCGTCGGTGCCATCGCCGGCTATCTGAGCCTGTGGGTCGTCTTCCAGCTGTTTCGGCTCGCGACCGGCAAGGAGG
GTCTGGGCTACGGCGACTTCAAGTTGTTGGCGCTGCTGGGCGCCTGGCTCGGCTGGACGGCGCTGCCGCAGATCATCCTG
CTCTCGGCCCTGGTCGGTGCCCTGGTCGGGATCGGACTGATCCTGAGCGGTCGGCACGCCTCGGACAAGCCACTGCCATT
CGGTCCCTATCTGGCCGCCGCCGGTTGGATCAGTCTGATCTGGGGCGAGTCGATCAATAACGCCTATCTGCGTCTGAGTG
GGCTCGGGTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (23-132)

• Type IV leader peptidase family (Peptidase_A24) (142-251)

3D structure

• AlphaFold DB: A0A6I6DWW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	51.211	97.635	0.5
pilD	Vibrio campbellii strain DS40M4	51.579	96.284	0.497
pilD	Acinetobacter nosocomialis M2	52.19	92.568	0.483
pilD	Acinetobacter baumannii D1279779	51.46	92.568	0.476
pilD	Neisseria gonorrhoeae MS11	47.584	90.878	0.432