Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   E5Q53_RS07000 Genome accession   NZ_CP038817
Coordinates   1449045..1449740 (+) Length   231 a.a.
NCBI ID   WP_005706936.1    Uniprot ID   A0AAE6MP49
Organism   Haemophilus parahaemolyticus strain NEB129     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1444045..1454740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5Q53_RS06970 (E5Q53_06965) - 1444761..1445387 (-) 627 WP_005706941.1 hypothetical protein -
  E5Q53_RS06975 (E5Q53_06970) radC 1445595..1446260 (-) 666 WP_005706985.1 DNA repair protein RadC -
  E5Q53_RS06980 (E5Q53_06975) coaBC 1446423..1447634 (+) 1212 WP_005706923.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  E5Q53_RS06985 (E5Q53_06980) dut 1447634..1448089 (+) 456 WP_005706994.1 dUTP diphosphatase -
  E5Q53_RS06990 (E5Q53_06985) slmA 1448135..1448743 (+) 609 WP_005706993.1 nucleoid occlusion factor SlmA -
  E5Q53_RS06995 (E5Q53_06990) - 1448753..1448974 (+) 222 WP_005706947.1 YheU family protein -
  E5Q53_RS07000 (E5Q53_06995) crp 1449045..1449740 (+) 696 WP_005706936.1 cAMP-activated global transcriptional regulator CRP Regulator
  E5Q53_RS07005 (E5Q53_07000) mutL 1449815..1451755 (-) 1941 WP_005706954.1 DNA mismatch repair endonuclease MutL -
  E5Q53_RS07010 (E5Q53_07005) proA 1451837..1453078 (+) 1242 WP_005706961.1 glutamate-5-semialdehyde dehydrogenase -
  E5Q53_RS07015 (E5Q53_07010) - 1453159..1454094 (+) 936 WP_005706965.1 KpsF/GutQ family sugar-phosphate isomerase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26220.40 Da        Isoelectric Point: 6.6937

>NTDB_id=355776 E5Q53_RS07000 WP_005706936.1 1449045..1449740(+) (crp) [Haemophilus parahaemolyticus strain NEB129]
MQDMMLSTPPIEDLTPAPSINDPVVEWFLTQCHVHRYPAKYTLIHAGEKAESLYYIVSGSVSVFVKDDEHKEMLLTNLGQ
GEFLGEISLFEEKLQTRTAWVKTKETCEIAEISYKRFKQIVHINPEILMYLSAQMARRLRQTSSQVSNLAFLDVAGRIAQ
TLMNLARQPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDDDLISAHGKTIVVFHKQLQKAMGV

Nucleotide


Download         Length: 696 bp        

>NTDB_id=355776 E5Q53_RS07000 WP_005706936.1 1449045..1449740(+) (crp) [Haemophilus parahaemolyticus strain NEB129]
ATGCAAGACATGATGCTTAGCACGCCTCCAATTGAGGATTTAACGCCTGCTCCATCTATCAATGATCCTGTGGTGGAATG
GTTCTTAACGCAATGCCACGTGCACCGCTACCCTGCAAAATATACATTGATCCATGCAGGCGAAAAGGCTGAATCGCTTT
ATTACATCGTAAGTGGTTCGGTGTCTGTTTTTGTTAAAGATGACGAGCATAAAGAAATGCTTTTAACCAACCTTGGACAG
GGTGAGTTTTTGGGCGAAATTAGTCTTTTTGAAGAAAAACTGCAAACTCGCACTGCTTGGGTGAAAACCAAAGAAACCTG
CGAAATTGCTGAGATTTCATACAAACGTTTCAAACAGATTGTACATATTAACCCTGAAATTTTGATGTATCTTTCTGCTC
AAATGGCACGCCGTTTACGCCAAACTTCGAGCCAAGTGAGCAATCTTGCGTTCCTAGATGTAGCGGGAAGAATTGCACAA
ACCTTGATGAATTTAGCTCGCCAACCTGATGCGATGACCCATCCAGAAGGAATGCAGATCAAGATCACCCGCCAGGAAAT
CGGTCAAATGGTCGGCTGTTCCCGAGAAACGGTTGGACGTATTCTAAAAATGCTTGAAGATGATGATCTGATTTCAGCTC
ACGGTAAAACGATTGTGGTGTTCCACAAGCAGCTACAGAAAGCGATGGGCGTATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(35-122)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

74

86.58

0.641
  crp Vibrio cholerae strain A1552

72.139

87.013

0.628
  crp Acinetobacter baumannii D1279779

46.798

87.879

0.411

Multiple sequence alignment