Detailed information NTG0355619

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: E5Q10_RS09845
• Genome accession: NZ_CP038808
• Coordinates: 1832606..1832908 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain R6CIB17
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1827606..1837908

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E5Q10_RS09815 (E5Q10_09810)	rnpA	1828285..1828656 (-)	372	WP_000739246.1	ribonuclease P protein component	-
E5Q10_RS11615	-	1828673..1828804 (-)	132	WP_000768904.1	hypothetical protein	-
E5Q10_RS09820 (E5Q10_09815)	-	1828805..1829995 (-)	1191	WP_000167757.1	acetate kinase	-
E5Q10_RS09825 (E5Q10_09820)	comYH	1830046..1830999 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
E5Q10_RS09830 (E5Q10_09825)	-	1831060..1831654 (-)	595	Protein_1830	class I SAM-dependent methyltransferase	-
E5Q10_RS09835 (E5Q10_09830)	comGG/cglG	1831791..1832204 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
E5Q10_RS09840 (E5Q10_09835)	comGF/cglF	1832182..1832643 (-)	462	WP_000250534.1	competence type IV pilus minor pilin ComGF	Machinery gene
E5Q10_RS09845 (E5Q10_09840)	comGE/cglE	1832606..1832908 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
E5Q10_RS09850 (E5Q10_09845)	comGD/cglD	1832871..1833275 (-)	405	WP_000588026.1	competence type IV pilus minor pilin ComGD	Machinery gene
E5Q10_RS09855 (E5Q10_09850)	comGC/cglC	1833268..1833594 (-)	327	WP_000738626.1	comG operon protein ComGC	Machinery gene
E5Q10_RS09860 (E5Q10_09855)	comGB/cglB	1833596..1834612 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
E5Q10_RS09865 (E5Q10_09860)	comGA/cglA/cilD	1834560..1835501 (-)	942	WP_000249564.1	competence type IV pilus ATPase ComGA	Machinery gene
E5Q10_RS09870 (E5Q10_09865)	-	1835577..1835942 (-)	366	WP_000286415.1	DUF1033 family protein	-
E5Q10_RS09875 (E5Q10_09870)	-	1836093..1837151 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=355619 E5Q10_RS09845 WP_000413382.1 1832606..1832908(-) (comGE/cglE) [Streptococcus pneumoniae strain R6CIB17]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=355619 E5Q10_RS09845 WP_000413382.1 1832606..1832908(-) (comGE/cglE) [Streptococcus pneumoniae strain R6CIB17]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4