Detailed information NTG0355622

Bioinformatically predicted

Overview

• Name: letA
• Type: Regulator
• Locus tag: GPY39_RS08290
• Genome accession: NZ_CP046783
• Coordinates: 1595873..1596517 (-)
• Length: 214 a.a.
• NCBI ID: WP_005386783.1
• Uniprot ID: Q87NC3
• Organism: Vibrio parahaemolyticus strain 2013V-1181
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1590873..1601517

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPY39_RS08280	pgsA	1593435..1593992 (-)	558	WP_005494716.1	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	-
GPY39_RS08285	uvrC	1594039..1595871 (-)	1833	WP_079765081.1	excinuclease ABC subunit UvrC	-
GPY39_RS08290	letA	1595873..1596517 (-)	645	WP_005386783.1	UvrY/SirA/GacA family response regulator transcription factor	Regulator
GPY39_RS08295	-	1597017..1599380 (+)	2364	WP_021448932.1	DNA polymerase II	-
GPY39_RS08300	-	1599377..1600144 (-)	768	WP_017448417.1	nucleotidyltransferase domain-containing protein	-
GPY39_RS08305	yeiP	1600331..1600897 (+)	567	WP_005465079.1	elongation factor P-like protein YeiP	-
GPY39_RS08310	-	1600900..1601220 (+)	321	WP_005465080.1	HI1450 family dsDNA-mimic protein	-

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 23765.32 Da
• Isoelectric Point: 5.6509

>NTDB_id=355622 GPY39_RS08290 WP_005386783.1 1595873..1596517(-) (letA) [Vibrio parahaemolyticus strain 2013V-1181]
MINVFLVDDHELVRTGIRRIIEDVRGMNVAGEADSGEDAVKWCRSNHADVVLMDMNMPGIGGLEATKKILRVNPDVKIIV
LTVHTENPFPTKVMQAGASGYLTKGAGPDEMVNAIRVVNSGQRYISPEIAQQMALSQFSPASENPFKDLSERELQIMLMI
TKGQKVTDISEQLNLSPKTVNSYRYRLFSKLDINGDVELTHLAIRHGMLDTETL

Nucleotide

• Length: 645 bp

>NTDB_id=355622 GPY39_RS08290 WP_005386783.1 1595873..1596517(-) (letA) [Vibrio parahaemolyticus strain 2013V-1181]
TTGATTAATGTTTTCCTTGTAGATGATCACGAGCTGGTTCGCACAGGGATACGACGTATTATTGAAGACGTCCGTGGAAT
GAACGTAGCAGGAGAAGCTGACAGCGGTGAAGATGCAGTGAAATGGTGTCGCAGTAATCATGCTGACGTCGTTTTAATGG
ACATGAACATGCCTGGGATTGGCGGCTTGGAAGCCACCAAGAAAATTCTTCGCGTGAATCCAGATGTGAAAATCATCGTA
CTAACCGTTCATACGGAAAATCCGTTTCCAACCAAAGTGATGCAGGCTGGTGCTTCTGGTTATTTAACCAAAGGTGCAGG
GCCGGATGAAATGGTAAATGCAATTCGTGTGGTCAATAGTGGGCAGCGTTACATCTCTCCAGAGATAGCGCAGCAAATGG
CATTGAGCCAGTTCTCACCAGCCTCTGAAAACCCATTTAAAGATTTGTCCGAACGTGAACTGCAAATCATGCTTATGATC
ACGAAAGGTCAGAAAGTAACGGATATTTCTGAGCAACTTAACTTAAGTCCAAAGACAGTCAACAGCTACCGCTATCGACT
GTTTAGCAAGCTGGACATTAATGGTGACGTTGAGTTAACACACTTAGCGATTCGCCACGGAATGCTGGACACCGAGACCC
TTTAG

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-116)

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

3D structure

• AlphaFold DB: Q87NC3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letA	Legionella pneumophila str. Paris	50.952	98.131	0.5
letA	Legionella pneumophila strain ERS1305867	50.952	98.131	0.5