Detailed information NTG0355583

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: E5Q10_RS04615
• Genome accession: NZ_CP038808
• Coordinates: 871668..872621 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain R6CIB17
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 866668..877621

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E5Q10_RS04590 (E5Q10_04590)	rpmG	867411..867560 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
E5Q10_RS04595 (E5Q10_04595)	secG	867600..867833 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
E5Q10_RS04600 (E5Q10_04600)	rnr	867935..870289 (+)	2355	WP_000654897.1	ribonuclease R	-
E5Q10_RS04605 (E5Q10_04605)	smpB	870252..870719 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
E5Q10_RS04610 (E5Q10_04610)	tehB	870735..871595 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
E5Q10_RS04615 (E5Q10_04615)	coiA	871668..872621 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
E5Q10_RS04620 (E5Q10_04620)	pepF	872640..874442 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
E5Q10_RS04625 (E5Q10_04625)	-	874444..875157 (+)	714	WP_000230399.1	O-methyltransferase	-
E5Q10_RS04630 (E5Q10_04630)	prsA	875224..876165 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
E5Q10_RS04635 (E5Q10_04635)	-	876284..876625 (-)	342	Protein_875	transposase	-
E5Q10_RS04645 (E5Q10_04645)	-	877037..877132 (+)	96	Protein_876	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=355583 E5Q10_RS04615 WP_000495911.1 871668..872621(+) (coiA) [Streptococcus pneumoniae strain R6CIB17]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=355583 E5Q10_RS04615 WP_000495911.1 871668..872621(+) (coiA) [Streptococcus pneumoniae strain R6CIB17]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435