Detailed information NTG0354061

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: GPA00_RS02180
• Genome accession: NZ_CP046629
• Coordinates: 433200..433889 (-)
• Length: 229 a.a.
• NCBI ID: WP_021143203.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU G6
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 428200..438889

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPA00_RS02155 (GPA00_02155)	dltC	428819..429058 (-)	240	WP_021143198.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-
GPA00_RS02160 (GPA00_02160)	dltB	429089..430351 (-)	1263	WP_157327356.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
GPA00_RS02165 (GPA00_02165)	dltA	430348..431883 (-)	1536	WP_157327358.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
GPA00_RS02170 (GPA00_02170)	-	431899..432021 (-)	123	WP_021143201.1	teichoic acid D-Ala incorporation-associated protein DltX	-
GPA00_RS02175 (GPA00_02175)	-	432022..433203 (-)	1182	WP_157327360.1	sensor histidine kinase	-
GPA00_RS02180 (GPA00_02180)	ciaR	433200..433889 (-)	690	WP_021143203.1	response regulator transcription factor	Regulator
GPA00_RS02185 (GPA00_02185)	-	434190..434984 (-)	795	WP_024344371.1	AraC family transcriptional regulator	-
GPA00_RS02190 (GPA00_02190)	bglS	435090..435731 (-)	642	WP_157327362.1	beta-glucanase	-
GPA00_RS02195 (GPA00_02195)	bglS	435750..437048 (-)	1299	WP_157327364.1	beta-glucanase	-
GPA00_RS02200 (GPA00_02200)	-	437072..437917 (-)	846	WP_021143207.1	carbohydrate ABC transporter permease	-
GPA00_RS02205 (GPA00_02205)	-	437917..438861 (-)	945	WP_045798424.1	carbohydrate ABC transporter permease	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26106.43 Da
• Isoelectric Point: 5.2074

>NTDB_id=354061 GPA00_RS02180 WP_021143203.1 433200..433889(-) (ciaR) [Streptococcus equinus strain CNU G6]
MRILVIEDEKGIAEAIQAILENHRYEVDIVFDGESGLDYILTGLYDLVLLDIMLPKLDGVSVLKRVRQMGIEVPIIFLTA
KSQLEDRVSGLDLGADDYMTKPFEAEELLARIRLRTRQSSITQVNHLKFGNLILNLDTRALSVLEHEVKLSNKEFLLMET
FLRNPQKIIPKNQLILKVWGPLDDSEYNQLEVFISFLRKKLRFLKADVAIKTTKGVGYSLECSVKEGDS

Nucleotide

• Length: 690 bp

>NTDB_id=354061 GPA00_RS02180 WP_021143203.1 433200..433889(-) (ciaR) [Streptococcus equinus strain CNU G6]
TTGAGAATATTAGTAATCGAGGATGAAAAAGGAATTGCTGAAGCGATTCAAGCTATTCTCGAAAATCATCGATATGAAGT
TGATATAGTTTTTGATGGAGAATCTGGTCTTGATTATATTTTAACAGGGCTTTATGATTTAGTCCTATTAGATATTATGT
TGCCTAAACTTGATGGTGTCAGTGTTTTAAAGCGAGTTCGTCAGATGGGAATAGAAGTACCAATCATTTTTTTGACAGCT
AAGTCTCAATTAGAAGATCGTGTGTCTGGTTTAGATTTGGGCGCAGATGATTATATGACTAAGCCATTTGAAGCTGAAGA
ACTATTAGCCAGGATTCGTTTGCGAACTCGGCAATCGTCAATTACTCAAGTTAATCACCTTAAATTTGGTAATTTAATAT
TGAATTTAGATACTAGAGCTTTAAGTGTTCTTGAGCACGAAGTGAAACTATCTAACAAAGAGTTCCTCTTAATGGAAACT
TTTTTACGCAATCCTCAGAAGATTATCCCCAAAAACCAATTGATTTTAAAAGTTTGGGGGCCGTTGGATGATTCAGAATA
TAATCAGCTTGAAGTTTTTATATCGTTTTTGAGGAAAAAGCTTCGTTTTTTAAAAGCTGATGTTGCTATTAAGACGACAA
AAGGTGTTGGCTATTCGCTTGAGTGTAGCGTGAAAGAAGGAGACTCATGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

• Response regulator receiver domain (Response_reg) (3-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	40.724	96.507	0.393
ciaR	Streptococcus pneumoniae D39	40.724	96.507	0.393
ciaR	Streptococcus pneumoniae R6	40.724	96.507	0.393
ciaR	Streptococcus pneumoniae TIGR4	40.724	96.507	0.393
ciaR	Streptococcus mutans UA159	39.819	96.507	0.384
covR	Lactococcus lactis subsp. lactis strain DGCC12653	37.668	97.38	0.367