Detailed information NTG0353981

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: GO596_RS03875
• Genome accession: NZ_CP046628
• Coordinates: 773375..774064 (+)
• Length: 229 a.a.
• NCBI ID: WP_021143203.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain CNU 77-23
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 768375..779064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO596_RS03850 (GO596_03850)	-	768404..769348 (+)	945	WP_045798424.1	carbohydrate ABC transporter permease	-
GO596_RS03855 (GO596_03855)	-	769348..770193 (+)	846	WP_021143207.1	carbohydrate ABC transporter permease	-
GO596_RS03860 (GO596_03860)	bglS	770217..771515 (+)	1299	WP_157339224.1	beta-glucanase	-
GO596_RS03865 (GO596_03865)	bglS	771534..772175 (+)	642	WP_157339225.1	beta-glucanase	-
GO596_RS03870 (GO596_03870)	-	772281..773075 (+)	795	WP_157339226.1	AraC family transcriptional regulator	-
GO596_RS03875 (GO596_03875)	ciaR	773375..774064 (+)	690	WP_021143203.1	response regulator transcription factor	Regulator
GO596_RS03880 (GO596_03880)	-	774061..775242 (+)	1182	WP_157339227.1	sensor histidine kinase	-
GO596_RS03885 (GO596_03885)	-	775243..775365 (+)	123	WP_021143201.1	teichoic acid D-Ala incorporation-associated protein DltX	-
GO596_RS03890 (GO596_03890)	dltA	775381..776916 (+)	1536	WP_157339228.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
GO596_RS03895 (GO596_03895)	dltB	776913..778175 (+)	1263	WP_157339229.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
GO596_RS03900 (GO596_03900)	dltC	778206..778445 (+)	240	WP_074629043.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26106.43 Da
• Isoelectric Point: 5.2074

>NTDB_id=353981 GO596_RS03875 WP_021143203.1 773375..774064(+) (ciaR) [Streptococcus equinus strain CNU 77-23]
MRILVIEDEKGIAEAIQAILENHRYEVDIVFDGESGLDYILTGLYDLVLLDIMLPKLDGVSVLKRVRQMGIEVPIIFLTA
KSQLEDRVSGLDLGADDYMTKPFEAEELLARIRLRTRQSSITQVNHLKFGNLILNLDTRALSVLEHEVKLSNKEFLLMET
FLRNPQKIIPKNQLILKVWGPLDDSEYNQLEVFISFLRKKLRFLKADVAIKTTKGVGYSLECSVKEGDS

Nucleotide

• Length: 690 bp

>NTDB_id=353981 GO596_RS03875 WP_021143203.1 773375..774064(+) (ciaR) [Streptococcus equinus strain CNU 77-23]
TTGAGAATATTAGTAATCGAGGATGAAAAAGGAATTGCTGAAGCGATTCAAGCTATTCTCGAAAATCATCGATATGAAGT
TGATATAGTTTTTGATGGAGAATCTGGTCTTGATTATATTTTAACAGGGCTTTATGATTTAGTCCTATTAGATATTATGT
TGCCTAAACTTGATGGTGTCAGTGTTTTAAAGCGAGTTCGTCAGATGGGCATAGAAGTACCAATCATTTTTTTGACAGCT
AAGTCTCAATTAGAAGATCGTGTGTCTGGTTTAGATTTGGGCGCAGATGATTATATGACTAAGCCATTTGAAGCTGAAGA
ACTATTAGCCAGGATTCGTTTGCGAACTCGGCAATCGTCAATTACTCAAGTTAATCACCTTAAATTTGGTAATTTAATAT
TGAATTTAGATACTAGAGCTTTAAGTGTTCTTGAGCACGAAGTGAAACTATCTAACAAAGAGTTCCTCTTAATGGAAACT
TTTTTACGCAATCCTCAGAAGATTATCCCCAAAAACCAATTGATTTTAAAAGTTTGGGGGCCGTTGGATGATTCAGAATA
TAATCAGCTTGAAGTTTTTATATCGTTTTTGAGGAAAAAGCTTCGTTTTTTAAAAGCTGATGTTGCTATTAAGACGACAA
AAGGTGTTGGCTATTCGCTTGAGTGTAGCGTGAAAGAAGGAGACTCATGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

• Response regulator receiver domain (Response_reg) (3-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	40.724	96.507	0.393
ciaR	Streptococcus pneumoniae D39	40.724	96.507	0.393
ciaR	Streptococcus pneumoniae R6	40.724	96.507	0.393
ciaR	Streptococcus pneumoniae TIGR4	40.724	96.507	0.393
ciaR	Streptococcus mutans UA159	39.819	96.507	0.384
covR	Lactococcus lactis subsp. lactis strain DGCC12653	37.668	97.38	0.367