Detailed information NTG0352944

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SaO55_RS13995
• Genome accession: NZ_CP038268
• Coordinates: 2691316..2692203 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain O55 isolate B118
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2686316..2697203

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SaO55_RS13960	-	2686319..2686411 (+)	93	WP_010956583.1	hypothetical protein	-
SaO55_RS13965 (SaO55_2579)	-	2686519..2687016 (-)	498	WP_001065267.1	glutathione peroxidase	-
SaO55_RS13970	-	2687026..2687286 (-)	261	WP_014532715.1	hypothetical protein	-
SaO55_RS13980	-	2687668..2687781 (-)	114	WP_072357681.1	hypothetical protein	-
SaO55_RS13985 (SaO55_2581)	-	2688456..2690456 (-)	2001	WP_000776732.1	ABC transporter permease	-
SaO55_RS13990 (SaO55_2582)	-	2690453..2691208 (-)	756	WP_044122909.1	ABC transporter ATP-binding protein	-
SaO55_RS13995 (SaO55_2583)	braS	2691316..2692203 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SaO55_RS14000	braR	2692214..2692879 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SaO55_RS14005 (SaO55_2585)	-	2692905..2693105 (-)	201	WP_000604727.1	hypothetical protein	-
SaO55_RS14010 (SaO55_2586)	-	2693303..2694727 (+)	1425	WP_000948997.1	alkaline phosphatase	-
SaO55_RS14660	-	2694787..2694888 (-)	102	WP_000731972.1	SE2200 family small protein	-
SaO55_RS14020 (SaO55_2587)	-	2695010..2695465 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SaO55_RS14025 (SaO55_2588)	-	2695710..2696471 (-)	762	WP_000323443.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=352944 SaO55_RS13995 WP_000143420.1 2691316..2692203(-) (braS) [Staphylococcus aureus strain O55 isolate B118]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=352944 SaO55_RS13995 WP_000143420.1 2691316..2692203(-) (braS) [Staphylococcus aureus strain O55 isolate B118]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993