Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   ES298_RS10945 Genome accession   NZ_CP038253
Coordinates   2122591..2123253 (-) Length   220 a.a.
NCBI ID   WP_000649971.1    Uniprot ID   A0A0B7MFB3
Organism   Streptococcus pneumoniae strain TVO_1901929     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2117591..2128253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES298_RS10920 (ES298_11510) - 2117741..2118007 (-) 267 WP_001278167.1 Veg family protein -
  ES298_RS10925 (ES298_11515) dnaB 2118009..2119361 (-) 1353 WP_000852486.1 replicative DNA helicase -
  ES298_RS10930 (ES298_11520) rplI 2119405..2119857 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  ES298_RS10935 (ES298_11525) - 2119854..2121827 (-) 1974 WP_000715116.1 DHH family phosphoesterase -
  ES298_RS10940 (ES298_11530) hpf 2121963..2122511 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ES298_RS10945 (ES298_11535) comFC/cflB 2122591..2123253 (-) 663 WP_000649971.1 ComF family protein Machinery gene
  ES298_RS10950 (ES298_11540) comFA/cflA 2123250..2124548 (-) 1299 WP_000867591.1 DEAD/DEAH box helicase Machinery gene
  ES298_RS10955 (ES298_11545) - 2124604..2125239 (+) 636 WP_000395738.1 YigZ family protein -
  ES298_RS10960 (ES298_11550) cysK 2125524..2126444 (+) 921 WP_000029866.1 cysteine synthase A -
  ES298_RS10965 (ES298_11560) - 2126519..2127057 (-) 539 Protein_2147 transposase -
  ES298_RS10970 (ES298_11565) - 2127030..2127338 (+) 309 Protein_2148 transposase -
  ES298_RS10975 (ES298_11570) tnpB 2127479..2127694 (-) 216 WP_000376909.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25241.10 Da        Isoelectric Point: 7.3688

>NTDB_id=352747 ES298_RS10945 WP_000649971.1 2122591..2123253(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901929]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=352747 ES298_RS10945 WP_000649971.1 2122591..2123253(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901929]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7MFB3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

100

100

1
  comFC/cflB Streptococcus pneumoniae Rx1

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae D39

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae R6

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

91.364

100

0.914

Multiple sequence alignment