Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GE024_RS10315 Genome accession   NZ_CP046521
Coordinates   2094244..2096226 (-) Length   660 a.a.
NCBI ID   WP_039994902.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2089244..2101226
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS10290 (GE024_10355) cinA 2090089..2091360 (-) 1272 WP_093999150.1 competence/damage-inducible protein A Machinery gene
  GE024_RS11340 - 2091477..2091635 (-) 159 WP_223824822.1 VOC family protein -
  GE024_RS10300 (GE024_10365) - 2091833..2092405 (-) 573 WP_003045731.1 DNA-3-methyladenine glycosylase I -
  GE024_RS10305 (GE024_10370) ruvA 2092415..2093011 (-) 597 WP_003045733.1 Holliday junction branch migration protein RuvA Machinery gene
  GE024_RS10310 (GE024_10375) - 2092995..2094233 (-) 1239 WP_003045734.1 MFS transporter -
  GE024_RS10315 (GE024_10380) hexB 2094244..2096226 (-) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL Machinery gene
  GE024_RS11290 - 2096320..2097244 (-) 925 Protein_1986 tyrosine-type recombinase/integrase -
  GE024_RS10330 (GE024_10395) - 2097859..2098434 (-) 576 WP_093999153.1 TMEM175 family protein -
  GE024_RS10335 (GE024_10400) - 2098495..2098983 (-) 489 WP_138114355.1 prolyl-tRNA synthetase associated domain-containing protein -
  GE024_RS10340 (GE024_10405) - 2099018..2099650 (-) 633 WP_093999155.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74407.98 Da        Isoelectric Point: 5.7465

>NTDB_id=352638 GE024_RS10315 WP_039994902.1 2094244..2096226(-) (hexB) [Streptococcus canis strain HL_100]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITIEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEAIHGSILVATGGKIETLEPISTPIGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIAIQLDPYLADVNVHPTKQEVRISKERELMALISA
AISESLREQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVAEKMPETDFHYGDVDNCVKVEK
TESLPHSEEDTGPSSVKHASRPQDSLVNPDHPDFDLKNKQKLSQMLDRLENEEKSAFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMTLLNEVGIFLEVYGHNTFILREHPIWMKEE
EIESGVYEMCDMLLLTNEVSVKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=352638 GE024_RS10315 WP_039994902.1 2094244..2096226(-) (hexB) [Streptococcus canis strain HL_100]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATCGCAGCTGGTGAGGTTGTAGAAAGACCAGCAAGTGT
TGTCAAGGAGTTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCATTGAAATTGAAGAGTCTGGCCTTAAAA
TGATACAGATTACAGACAATGGTGAAGGGATGTCACACGAAGACCTACCCTTGAGTTTGCGTCGTCATGCCACCAGTAAA
ATTAAAAGTCAGAGTGACCTTTTTCGAATTAGGACGCTTGGATTTCGAGGAGAAGCTTTACCGTCGGTTGCCTCCATTAG
TAAAATCACGATAAAAACTGCAACAAAAGAAGCTATACATGGCTCTATTCTCGTTGCTACGGGTGGGAAAATTGAGACGC
TTGAACCAATCTCAACACCTATTGGAACTAAAATTAAGGTTGAAAACCTTTTTTACAACACTCCTGCCCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAATCGGTTGAGTTTGGCTCACCCAGAAGTTGCTTT
TACACTGATTAGTGATGGTCGTCAATTAACTCAGACCTCAGGGACTGGCGATTTGCGCCAAGCTATTGCTGGTATTTACG
GCTTGAATACTGCGAAGAAAATGATTGCTATCTCTAATGCTGATCTGGATTTTGAAGTGTCTGGATATGTCAGTTTACCA
GAGTTGACACGTGCTAATCGAAACTATATGACAATTTTAATCAACGGACGCTACATTAAAAACTTCTTGCTCAATCGAGC
TATCTTAGATGGTTATGGTTCTAAATTGATGGTTGGACGTTTTCCGATTGTTGTGATTGCTATTCAGCTTGATCCTTACT
TAGCTGATGTCAATGTGCACCCCACAAAGCAAGAGGTTCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATCAGTGCA
GCTATTTCTGAAAGCCTTAGGGAACAAGATTTAATTCCAGATGCACTTGAAAATTTAGCTAAATCAAGCACACGACATTT
TTCCAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTACTATGATCCGCAAAAGAATGACTTTTTTGTCA
AAGAATCGGCTGTCGCGGAAAAAATGCCTGAAACTGATTTTCATTACGGCGATGTTGACAACTGTGTAAAGGTTGAAAAG
ACAGAGTCGCTACCTCACTCAGAAGAAGACACAGGACCTTCTTCAGTAAAGCATGCTAGCCGTCCCCAAGATAGTTTAGT
GAATCCTGATCATCCTGACTTTGACTTAAAAAATAAACAGAAGTTATCTCAAATGTTGGATCGCTTGGAAAATGAAGAAA
AATCAGCATTTCCTGAATTGGATTATTTTGGTCAGATGCATGGGACCTATCTTTTTGCTCAAGGCAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATATGAATATTATCGTGATAAGATTGGCGATGTTGACAGTAGTTT
ACAGCAGTTGTTAGTGCCTTACTTATTTGAGTTTTCTGGTTCTGATTTCATTAATTTACAGGAAAAAATGACACTCTTAA
ATGAAGTCGGTATCTTTCTGGAAGTTTATGGGCACAATACTTTCATTCTGAGGGAACACCCTATCTGGATGAAAGAAGAA
GAGATTGAATCTGGTGTCTATGAAATGTGTGATATGTTACTTTTGACAAATGAGGTATCTGTCAAAACTTATCGAGCAGA
GTTAGCGATTATGATGAGCTGTAAACGGTCTATTAAAGCTAATCACAGTTTAGATGATTATTCAGCAAGGAATCTTTTGC
TGCAATTAGCGCAATGCCAAAATCCTTATAACTGTCCTCATGGCAGACCCGTTTTGATTAACTTTAGCAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGTCTACGAGAATTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.477

100

0.688

Multiple sequence alignment