Detailed information NTG0352617

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: ES276_RS02585
• Genome accession: NZ_CP038252
• Coordinates: 471347..472006 (-)
• Length: 219 a.a.
• NCBI ID: WP_000565004.1
• Uniprot ID: A0AA95DDC2
• Organism: Streptococcus pneumoniae strain TVO_1901936
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 466347..477006

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES276_RS02555 (ES276_02715)	-	466474..467040 (+)	567	WP_000601930.1	aminodeoxychorismate/anthranilate synthase component II	-
ES276_RS02560 (ES276_02720)	trpD	467051..468055 (+)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
ES276_RS02565 (ES276_02725)	trpC	468052..468819 (+)	768	WP_238093044.1	indole-3-glycerol phosphate synthase TrpC	-
ES276_RS02570 (ES276_02730)	-	468806..469405 (+)	600	WP_000169890.1	phosphoribosylanthranilate isomerase	-
ES276_RS02575 (ES276_02735)	trpB	469383..470606 (+)	1224	WP_000331289.1	tryptophan synthase subunit beta	-
ES276_RS02580 (ES276_02740)	trpA	470599..471375 (+)	777	WP_001127029.1	tryptophan synthase subunit alpha	-
ES276_RS02585 (ES276_02745)	cclA/cilC	471347..472006 (-)	660	WP_000565004.1	A24 family peptidase	Machinery gene
ES276_RS02590 (ES276_02750)	-	472076..472522 (+)	447	WP_000155427.1	GNAT family N-acetyltransferase	-
ES276_RS02595 (ES276_02755)	-	472700..472939 (+)	240	WP_001005784.1	transposase	-
ES276_RS02600 (ES276_02760)	-	473049..473252 (-)	204	WP_000109957.1	CsbD family protein	-
ES276_RS02605 (ES276_02765)	-	473283..473891 (-)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
ES276_RS02610 (ES276_02770)	-	473930..474100 (-)	171	WP_000455066.1	DUF2273 domain-containing protein	-
ES276_RS02615 (ES276_02775)	amaP	474112..474678 (-)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
ES276_RS02620 (ES276_02780)	-	474762..474926 (-)	165	WP_001808603.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
ES276_RS02625 (ES276_02785)	mgaSpn	475369..476850 (+)	1482	WP_001205280.1	virulence factor transcriptional regulator MgaSpn	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24842.93 Da
• Isoelectric Point: 7.6165

>NTDB_id=352617 ES276_RS02585 WP_000565004.1 471347..472006(-) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901936]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLG
LLFLLYSWGWLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=352617 ES276_RS02585 WP_000565004.1 471347..472006(-) (cclA/cilC) [Streptococcus pneumoniae strain TVO_1901936]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAAGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGGATGGCTCTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCAGCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	100	100	1
cclA/cilC	Streptococcus pneumoniae Rx1	94.977	100	0.95
cclA/cilC	Streptococcus pneumoniae D39	94.977	100	0.95
cclA/cilC	Streptococcus pneumoniae R6	94.977	100	0.95
cclA/cilC	Streptococcus mitis SK321	91.781	100	0.918
cclA/cilC	Streptococcus mitis NCTC 12261	87.215	100	0.872