Detailed information NTG0352603

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: GE024_RS07355
• Genome accession: NZ_CP046521
• Coordinates: 1451010..1453253 (-)
• Length: 747 a.a.
• NCBI ID: WP_093998770.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_100
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1446010..1458253

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE024_RS07330 (GE024_07345)	-	1446627..1447847 (+)	1221	WP_093998767.1	DUF3114 domain-containing protein	-
GE024_RS07335 (GE024_07350)	-	1447961..1449022 (-)	1062	WP_171004473.1	serine hydrolase	-
GE024_RS07345 (GE024_07360)	sodA	1449188..1449793 (-)	606	WP_003044189.1	superoxide dismutase SodA	-
GE024_RS07350 (GE024_07365)	holA	1449890..1450930 (-)	1041	WP_093998769.1	DNA polymerase III subunit delta	-
GE024_RS07355 (GE024_07370)	comEC/celB	1451010..1453253 (-)	2244	WP_093998770.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
GE024_RS07360 (GE024_07375)	comEA	1453234..1453896 (-)	663	WP_093998771.1	ComEA family DNA-binding protein	Machinery gene
GE024_RS07365 (GE024_07380)	-	1454099..1454839 (-)	741	WP_003044195.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
GE024_RS07370 (GE024_07385)	-	1454957..1455733 (+)	777	WP_093998772.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
GE024_RS07375 (GE024_07390)	-	1455723..1456001 (+)	279	WP_003044201.1	GIY-YIG nuclease family protein	-
GE024_RS07380 (GE024_07395)	-	1456129..1458129 (-)	2001	WP_156667763.1	potassium transporter Kup	-

Sequence

Protein

• Length: 747 a.a.
• Molecular weight: 85139.05 Da
• Isoelectric Point: 9.7311

>NTDB_id=352603 GE024_RS07355 WP_093998770.1 1451010..1453253(-) (comEC/celB) [Streptococcus canis strain HL_100]
MTFSWTKLLPLPKIQLAFLVLVLFYHIYSPSWLTSLLSLGLICLLVKRLSKREFLSVFALLSLCALFLLYQKQQLTQELE
IQPVQITSVELIPDSIRINGDQLAVIGRHGKHSYQLFYRLKSQAEAQLFKKEHRWLVLHAKVTLEKAEEVRNFKGFNYQT
FLAYQGIYRIGKVEQMEQLEVSSPKSVFDYLSSLRRQAIVHCQQHFPKPMSHYLTGLLFGYLDKSFGEMTDYYSQLGIIH
LFALSGMQVGFFLTYFRRLLLLLAVPLEWIKWIELPFACFYAALTGYSISVIRSLVQSQLRHLGIKGLDNLACTFLLVFL
WDAHFLMTVGGVLTFSYAFMLTIVTVEELSGAKRQLVQALIISLGMLPLLLFYFSSFNPMSIILTGLLSYLFDVLILPLL
CLVFCLSPLVTVSVCNHLFLLLEKGIQFLGNTVNTSLVFGSPTSWQLLLIVLSFAILYDYRQVRQRVFACGLVIALTLLS
VKYPLTNEVTIVDIGQGDSILIRDWRGKTLLIDVGGRPTFSKKEKWRSGYQTANAQRTLIPYLKSRGIHKIDQLLLTHTD
ADHMGDMEVVAKAIRVKEVLTSQGSLTNPSAVQRLNRLKCQVKVVKAGDQLSIMGSTLQVLYPWKLGDGKNNDSLVLYGK
LLNRTFLFTGDLEKEGEVEIIKRYPQLRVDYLKAGHHGSNTSSSAVFLDHLQPKLAFISAGKNNRYHHPSKETLTRLEDR
QITYYRTDTQGAIRLTGWTSWHLETVR

Nucleotide

• Length: 2244 bp

>NTDB_id=352603 GE024_RS07355 WP_093998770.1 1451010..1453253(-) (comEC/celB) [Streptococcus canis strain HL_100]
ATGACATTTTCTTGGACTAAGCTATTGCCCCTGCCAAAGATTCAATTAGCTTTTTTGGTTTTGGTTCTCTTTTATCACAT
TTATAGTCCTAGCTGGTTAACTTCTCTTCTTAGTCTTGGTTTGATTTGCTTACTTGTAAAGCGTTTGTCTAAAAGAGAAT
TTCTCAGTGTTTTTGCCCTCCTTAGTTTATGTGCTTTGTTCTTACTCTATCAGAAACAACAGCTGACCCAAGAACTGGAA
ATTCAGCCAGTACAAATAACCTCTGTAGAATTGATTCCTGATAGTATTCGGATTAATGGTGATCAATTAGCTGTTATTGG
ACGTCATGGGAAACACTCCTATCAGTTATTTTACCGTTTGAAAAGCCAAGCAGAAGCCCAATTGTTCAAAAAAGAACACC
GTTGGTTAGTGCTGCACGCAAAAGTGACCTTGGAAAAAGCTGAGGAGGTTCGCAATTTTAAAGGATTTAATTACCAGACT
TTTTTGGCTTATCAGGGAATTTACAGAATAGGAAAGGTAGAGCAAATGGAACAGCTTGAAGTGAGCTCTCCAAAGTCAGT
GTTTGATTACTTGTCTTCTTTAAGACGGCAGGCCATTGTCCATTGTCAACAGCATTTTCCTAAACCCATGTCACACTACC
TGACAGGTCTCCTTTTTGGTTATTTAGATAAGTCGTTTGGTGAGATGACAGATTATTATAGCCAGCTGGGCATCATTCAT
CTCTTTGCCTTATCAGGGATGCAGGTTGGTTTTTTTCTCACTTATTTTAGAAGGTTGTTGCTATTACTAGCAGTTCCTTT
GGAATGGATAAAATGGATAGAGCTTCCTTTTGCTTGCTTTTATGCCGCGCTGACAGGTTATAGTATTTCTGTTATTCGAA
GCCTCGTGCAGTCGCAGTTGCGTCATTTAGGCATAAAAGGTTTAGACAATCTCGCTTGTACTTTTTTACTTGTCTTTTTA
TGGGATGCCCATTTCTTAATGACTGTTGGTGGGGTATTAACATTTAGCTATGCTTTTATGTTAACAATAGTTACTGTTGA
AGAATTATCAGGAGCTAAAAGACAGTTGGTACAAGCGCTAATTATTTCCCTAGGAATGTTACCGTTACTGCTGTTTTATT
TTTCCAGTTTTAATCCGATGTCAATAATATTAACAGGTCTCTTGTCTTACCTCTTTGACGTTTTGATTTTGCCTCTTCTT
TGTCTGGTTTTCTGTCTATCCCCTCTGGTGACTGTCTCAGTATGCAATCATCTCTTTCTTTTATTAGAAAAGGGGATTCA
ATTTCTTGGAAATACTGTCAATACTTCCCTTGTTTTTGGAAGTCCAACTAGTTGGCAATTACTTCTTATAGTGCTCAGCT
TTGCGATTCTTTATGACTATCGACAGGTGCGACAAAGGGTCTTCGCTTGTGGATTGGTCATAGCATTGACCTTACTGTCT
GTCAAATACCCTTTGACAAATGAAGTCACTATCGTTGATATTGGACAAGGAGATAGTATTTTGATAAGGGATTGGCGAGG
AAAGACACTCTTGATAGACGTTGGAGGACGTCCAACCTTTTCTAAAAAGGAGAAATGGCGCAGCGGTTATCAGACGGCGA
ATGCCCAAAGAACCTTAATCCCTTATTTAAAAAGCAGAGGCATTCATAAAATTGATCAGTTATTACTAACTCATACGGAT
GCTGATCACATGGGAGATATGGAAGTGGTTGCCAAAGCCATTCGAGTGAAGGAAGTGTTAACTAGCCAAGGTAGTTTAAC
GAACCCAAGTGCTGTGCAACGTTTAAACCGTTTAAAATGTCAGGTTAAGGTTGTTAAAGCTGGCGACCAGTTGTCCATTA
TGGGAAGCACCTTGCAGGTCCTCTATCCTTGGAAACTAGGAGATGGAAAAAATAATGATTCTTTGGTCCTCTATGGCAAG
CTATTAAATCGAACTTTTCTTTTCACAGGGGACTTGGAAAAAGAAGGAGAAGTTGAGATTATCAAACGTTATCCCCAGTT
AAGGGTGGATTATTTGAAAGCTGGCCATCATGGGTCAAATACTTCTTCAAGTGCAGTTTTTTTAGACCATCTTCAGCCCA
AGCTTGCTTTTATTTCTGCAGGAAAGAATAATCGGTACCACCATCCTAGTAAAGAGACCTTAACACGTTTGGAAGACAGA
CAAATCACGTATTATCGAACTGATACTCAAGGAGCTATTCGTTTGACTGGTTGGACCAGCTGGCATCTTGAAACGGTCCG
TTAG

Domains

Predicted by InterProScan.

• Competence protein (Competence) (217-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (495-696)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	47.193	100	0.473
comEC/celB	Streptococcus mitis NCTC 12261	47.051	99.866	0.47
comEC/celB	Streptococcus pneumoniae Rx1	45.588	100	0.456
comEC/celB	Streptococcus pneumoniae D39	45.588	100	0.456
comEC/celB	Streptococcus pneumoniae R6	45.588	100	0.456
comEC/celB	Streptococcus pneumoniae TIGR4	45.649	100	0.456
comEC	Lactococcus lactis subsp. cremoris KW2	42.013	99.732	0.419