Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   GL188_RS00125 Genome accession   NZ_CP046359
Coordinates   24627..24863 (+) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 573     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 19627..29863
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL188_RS00115 (GL188_00115) - 22683..23529 (+) 847 Protein_17 IS630 family transposase -
  GL188_RS00120 (GL188_00120) - 23564..24361 (-) 798 Protein_18 transposase -
  GL188_RS00125 (GL188_00125) comW 24627..24863 (+) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  GL188_RS00130 (GL188_00130) - 25094..26380 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  GL188_RS00135 (GL188_00135) tadA 26581..27048 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  GL188_RS10815 (GL188_00145) - 27257..27955 (-) 699 WP_001106362.1 tyrosine-type recombinase/integrase -
  GL188_RS10820 (GL188_00150) - 28045..28392 (-) 348 WP_001839379.1 hypothetical protein -
  GL188_RS00150 (GL188_00155) - 28453..29523 (-) 1071 WP_000401841.1 type I restriction endonuclease -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=351185 GL188_RS00125 WP_000939544.1 24627..24863(+) (comW) [Streptococcus pneumoniae strain 573]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=351185 GL188_RS00125 WP_000939544.1 24627..24863(+) (comW) [Streptococcus pneumoniae strain 573]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974
  comW Streptococcus pneumoniae D39

97.436

100

0.974
  comW Streptococcus pneumoniae R6

97.436

100

0.974
  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974
  comW Streptococcus mitis SK321

78.205

100

0.782
  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769