Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   E2L09_RS12150 Genome accession   NZ_CP037955
Coordinates   2571410..2572657 (-) Length   415 a.a.
NCBI ID   WP_088775066.1    Uniprot ID   -
Organism   Enterococcus hirae strain CQP3-9     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2566410..2577657
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E2L09_RS12140 (E2L09_12170) rny 2568139..2569695 (-) 1557 WP_010720620.1 ribonuclease Y -
  E2L09_RS12145 (E2L09_12175) recA 2570265..2571305 (-) 1041 WP_010720621.1 recombinase RecA Machinery gene
  E2L09_RS12150 (E2L09_12180) cinA 2571410..2572657 (-) 1248 WP_088775066.1 competence/damage-inducible protein A Machinery gene
  E2L09_RS12155 (E2L09_12185) pgsA 2572973..2573551 (-) 579 WP_010720623.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E2L09_RS12160 (E2L09_12190) - 2573721..2574611 (-) 891 WP_010720624.1 RodZ domain-containing protein -
  E2L09_RS12165 (E2L09_12195) - 2574842..2576131 (-) 1290 WP_088775067.1 pitrilysin family protein -
  E2L09_RS12170 (E2L09_12200) - 2576124..2577392 (-) 1269 WP_160231917.1 pitrilysin family protein -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 45717.08 Da        Isoelectric Point: 4.6797

>NTDB_id=351004 E2L09_RS12150 WP_088775066.1 2571410..2572657(-) (cinA) [Enterococcus hirae strain CQP3-9]
MKSEIIAVGTELLLGQVVNTNATFLSEQLADLGIDVYYQTVVGDNPDRLESLLQLAETRSDLIILCGGLGPTEDDLTKEV
TAKHLGEELIQNTEGYKKLLAFFETTKRKMTENNLQQSQIIDGGIALPNRTGLALGTFYQTADHVYLLLPGPPSELKPMF
IEQARPLLEQNFPSEEMLISKVLRFYGIGESQLVTELKDLIETQINPTIAPYAKPNEVTLRLTVKTKDKHAGNQALLALE
EKVLARVGEYFYGYGDDNSLPKVVVELLKERNQTITAAESLTAGAFQSALGEISGVSQVFPGGFITYSLETKAEFLNIDD
ALLKQHGTVSQECAEQMAIQARNLAKTDYAISFTGVAGPDTLEGQPAGTVWIAVATSEGEVISQKYQFTRDRSHIRNSAV
MQGFDLIRRQLLRKK

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=351004 E2L09_RS12150 WP_088775066.1 2571410..2572657(-) (cinA) [Enterococcus hirae strain CQP3-9]
ATGAAATCAGAAATCATAGCAGTAGGGACAGAACTTTTACTAGGACAAGTAGTCAACACGAATGCCACGTTTTTATCCGA
ACAGTTAGCAGACCTCGGGATTGATGTGTATTATCAAACGGTGGTTGGTGATAATCCCGACCGCTTAGAATCATTACTCC
AATTAGCAGAAACCAGAAGTGACTTGATCATTTTATGTGGAGGGTTGGGACCGACAGAAGACGACCTGACGAAAGAAGTT
ACTGCGAAACATCTAGGGGAAGAATTGATCCAAAACACCGAAGGCTATAAAAAATTGTTAGCATTTTTTGAAACGACCAA
GCGTAAAATGACTGAAAACAATTTACAACAATCACAAATCATCGATGGGGGGATTGCTTTACCTAATCGCACAGGCTTAG
CATTAGGTACGTTCTATCAAACAGCAGACCATGTCTATCTCTTGTTACCTGGACCACCGAGTGAATTAAAGCCAATGTTC
ATTGAACAAGCTCGCCCATTATTGGAGCAAAACTTTCCATCTGAAGAAATGCTGATCTCAAAAGTTTTACGTTTTTACGG
TATCGGGGAATCCCAACTAGTCACAGAATTAAAAGACTTGATTGAAACACAGATCAACCCAACGATTGCCCCTTACGCAA
AACCTAACGAAGTCACTTTACGATTAACTGTGAAGACCAAAGACAAACATGCAGGAAACCAAGCCTTACTTGCTTTGGAA
GAAAAAGTATTGGCGAGAGTAGGTGAGTACTTCTATGGATATGGTGATGATAATTCATTGCCTAAAGTGGTCGTAGAATT
ATTAAAGGAAAGAAACCAAACAATTACTGCAGCAGAAAGTTTGACTGCTGGAGCCTTTCAATCAGCTTTGGGAGAGATCT
CTGGTGTTTCTCAAGTCTTCCCAGGAGGCTTCATTACCTATTCTTTAGAAACTAAAGCAGAATTTTTAAACATCGATGAT
GCACTATTGAAGCAGCATGGAACCGTCAGCCAAGAATGTGCAGAACAAATGGCTATCCAAGCACGTAATTTAGCAAAAAC
AGATTATGCGATTTCGTTTACTGGAGTGGCTGGACCAGATACCTTAGAAGGACAGCCAGCTGGAACAGTTTGGATCGCGG
TTGCAACAAGTGAAGGGGAGGTCATTTCGCAGAAATACCAATTTACCAGAGACCGTTCTCATATAAGGAATAGCGCAGTA
ATGCAAGGATTTGATCTCATTAGAAGACAACTATTAAGAAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-411)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

53.828

100

0.542
  cinA Streptococcus pneumoniae TIGR4

52.381

100

0.53
  cinA Streptococcus pneumoniae Rx1

52.143

100

0.528
  cinA Streptococcus pneumoniae R6

52.143

100

0.528
  cinA Streptococcus mitis SK321

52.143

100

0.528
  cinA Streptococcus pneumoniae D39

52.143

100

0.528
  cinA Streptococcus mitis NCTC 12261

51.667

100

0.523
  cinA Bacillus subtilis subsp. subtilis str. 168

47.458

99.518

0.472
  cinA Streptococcus suis isolate S10

42.857

100

0.434

Multiple sequence alignment