Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   GLO74_RS10750 Genome accession   NZ_CP046354
Coordinates   2097296..2097532 (-) Length   78 a.a.
NCBI ID   WP_000939544.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 310     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 2092296..2102532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO74_RS10725 (GLO74_10925) - 2092636..2093706 (+) 1071 WP_000401841.1 type I restriction endonuclease -
  GLO74_RS11230 (GLO74_10930) - 2093767..2094114 (+) 348 WP_001839379.1 hypothetical protein -
  GLO74_RS11235 (GLO74_10935) - 2094204..2094902 (+) 699 WP_001106362.1 tyrosine-type recombinase/integrase -
  GLO74_RS10740 (GLO74_10945) tadA 2095111..2095578 (-) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  GLO74_RS10745 (GLO74_10950) - 2095779..2097065 (-) 1287 WP_000205044.1 adenylosuccinate synthase -
  GLO74_RS10750 (GLO74_10955) comW 2097296..2097532 (-) 237 WP_000939544.1 sigma(X)-activator ComW Regulator
  GLO74_RS10755 (GLO74_10960) - 2097798..2098595 (+) 798 Protein_2099 transposase -
  GLO74_RS10760 (GLO74_10965) - 2098630..2099476 (-) 847 Protein_2100 IS630 family transposase -

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9667.10 Da        Isoelectric Point: 6.4701

>NTDB_id=350698 GLO74_RS10750 WP_000939544.1 2097296..2097532(-) (comW) [Streptococcus pneumoniae strain 310]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCHRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=350698 GLO74_RS10750 WP_000939544.1 2097296..2097532(-) (comW) [Streptococcus pneumoniae strain 310]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCATAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

78.205

100

0.782

  comW Streptococcus mitis NCTC 12261

77.922

98.718

0.769