Detailed information NTG0035011

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: MGAS15252_RS00265
• Genome accession: NC_017040
• Coordinates: 48239..49237 (+)
• Length: 332 a.a.
• NCBI ID: WP_014407198.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS15252
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 43239..54237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS15252_RS00250 (MGAS15252_0053)	-	44241..45659 (+)	1419	WP_011888524.1	hypothetical protein	-
MGAS15252_RS00255 (MGAS15252_0054)	purB	45679..46971 (+)	1293	WP_014407197.1	adenylosuccinate lyase	-
MGAS15252_RS00260 (MGAS15252_0055)	comR	47102..48013 (+)	912	WP_002986681.1	transcriptional regulator Rgg4/ComR	Regulator
MGAS15252_RS09320	comS	48097..48192 (+)	96	WP_198462994.1	quorum-sensing system DWW-type pheromone	Regulator
MGAS15252_RS00265 (MGAS15252_0056)	ruvB	48239..49237 (+)	999	WP_014407198.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
MGAS15252_RS00270 (MGAS15252_0057)	-	49375..49812 (+)	438	WP_002994668.1	low molecular weight protein-tyrosine-phosphatase	-
MGAS15252_RS00275 (MGAS15252_0058)	-	49835..50236 (+)	402	WP_012560369.1	MORN repeat-containing protein	-
MGAS15252_RS00280 (MGAS15252_0059)	-	50233..52008 (+)	1776	WP_014407199.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37581.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=35011 MGAS15252_RS00265 WP_014407198.1 48239..49237(+) (ruvB) [Streptococcus pyogenes MGAS15252]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
SQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=35011 MGAS15252_RS00265 WP_014407198.1 48239..49237(+) (ruvB) [Streptococcus pyogenes MGAS15252]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCCGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATCTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTTGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
TCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473