Detailed information NTG0350105

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: GJV39_RS09595
• Genome accession: NZ_CP046114
• Coordinates: 1906599..1907273 (+)
• Length: 224 a.a.
• NCBI ID: WP_010787261.1
• Uniprot ID: B8F851
• Organism: Glaesserella parasuis strain SCW0912
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1901599..1912273

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJV39_RS09555 (GJV39_09555)	rpmG	1902237..1902407 (-)	171	WP_005624479.1	50S ribosomal protein L33	-
GJV39_RS09560 (GJV39_09560)	rpmB	1902419..1902655 (-)	237	WP_006251446.1	50S ribosomal protein L28	-
GJV39_RS09565 (GJV39_09565)	radC	1902781..1903497 (-)	717	WP_005713175.1	RadC family protein	Machinery gene
GJV39_RS09570 (GJV39_09570)	coaBC	1903667..1904869 (+)	1203	WP_021110350.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
GJV39_RS09575 (GJV39_09575)	-	1904879..1905205 (+)	327	WP_005713172.1	hypothetical protein	-
GJV39_RS09580 (GJV39_09580)	dut	1905231..1905686 (+)	456	WP_021110349.1	dUTP diphosphatase	-
GJV39_RS09585 (GJV39_09585)	slmA	1905695..1906300 (+)	606	WP_005713169.1	nucleoid occlusion factor SlmA	-
GJV39_RS09590 (GJV39_09590)	-	1906308..1906532 (+)	225	WP_005713165.1	YheU family protein	-
GJV39_RS09595 (GJV39_09595)	crp	1906599..1907273 (+)	675	WP_010787261.1	cAMP-activated global transcriptional regulator CRP	Regulator
GJV39_RS09600 (GJV39_09600)	-	1907528..1907779 (+)	252	WP_223300025.1	hypothetical protein	-
GJV39_RS09605 (GJV39_09605)	-	1907818..1907964 (+)	147	WP_021110348.1	hypothetical protein	-
GJV39_RS09610 (GJV39_09610)	pyrD	1908172..1909179 (-)	1008	WP_021110347.1	quinone-dependent dihydroorotate dehydrogenase	-
GJV39_RS12290	-	1909183..1909428 (+)	246	WP_035498265.1	hypothetical protein	-
GJV39_RS09615 (GJV39_09615)	-	1909429..1910379 (-)	951	WP_005713153.1	ribose-phosphate pyrophosphokinase	-
GJV39_RS09620 (GJV39_09620)	ispE	1910407..1911252 (-)	846	WP_021110346.1	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	-
GJV39_RS09625 (GJV39_09625)	lolB	1911254..1911886 (-)	633	WP_021110345.1	lipoprotein insertase outer membrane protein LolB	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25208.17 Da
• Isoelectric Point: 6.9079

>NTDB_id=350105 GJV39_RS09595 WP_010787261.1 1906599..1907273(+) (crp) [Glaesserella parasuis strain SCW0912]
MQDVSISTAQLEDVSPLPSIHDPSVEWFLTHCHIHRYPAKYTLIHAGEDAESLFYIVSGAVSVFIKDEEGKEMLLTNLGQ
GEFVGEISLFEEKAQPRTAWVRTKGNCEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRMTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPQGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=350105 GJV39_RS09595 WP_010787261.1 1906599..1907273(+) (crp) [Glaesserella parasuis strain SCW0912]
ATGCAAGATGTTTCAATCTCAACCGCACAGCTTGAAGATGTCAGCCCATTACCATCCATTCACGATCCTTCGGTGGAATG
GTTTTTAACTCACTGTCATATTCATCGTTATCCAGCAAAATATACTTTAATTCACGCAGGTGAAGATGCTGAATCACTGT
TTTATATTGTCAGCGGAGCTGTGTCTGTCTTTATCAAGGATGAAGAAGGCAAGGAGATGTTATTAACCAATTTAGGACAA
GGCGAATTTGTCGGTGAAATCAGCCTTTTTGAAGAAAAGGCTCAGCCTCGCACTGCTTGGGTAAGAACTAAAGGCAACTG
TGAAATTGCTGAAATTTCTTATAAAAAATTCAAGCAATTAGTTCATCTAAATCCTGATATCTTAATGTATCTCTCAGCTC
AGATGGCTCGCCGTTTACGAATGACATCAAGACAGGTTAGTAACCTTGCATTCCTTGATGTAACAGGCCGTATTGCTCAA
ACATTGATGAATTTAGCTAAAATGCCTGATGCGATGACTCACCCTCAGGGTATGCAGATTAAAATTACTCGCCAAGAAAT
TGGTCAAATGGTTGGTTGCTCACGAGAAACTGTAGGCCGTATTTTGAAAATGCTTGAGGATGAAGGGTTAATTTCTGCAC
ATGGTAAAACTATCGTTGTGTATGGGACAAGATAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (35-121)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

3D structure

• AlphaFold DB: B8F851

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	75.862	90.625	0.687
crp	Haemophilus influenzae Rd KW20	73.399	90.625	0.665
crp	Acinetobacter baumannii D1279779	48.5	89.286	0.433