Detailed information
Bioinformatically predicted
Overview
| Name | recA | Type | Machinery gene |
| Locus tag | E1H37_RS07230 | Genome accession | NZ_CP037818 |
| Coordinates | 1473867..1474913 (+) | Length | 348 a.a. |
| NCBI ID | WP_021364420.1 | Uniprot ID | A0A9X8RFQ1 |
| Organism | Clostridioides difficile strain Cd14 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1447819..1512653 | 1473867..1474913 | within | 0 |
Gene organization within MGE regions
Location: 1447819..1512653
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E1H37_RS07115 (E1H37_07230) | rimP | 1450235..1450696 (+) | 462 | WP_003438303.1 | ribosome maturation factor RimP | - |
| E1H37_RS07120 (E1H37_07235) | nusA | 1450726..1451880 (+) | 1155 | WP_003428238.1 | transcription termination factor NusA | - |
| E1H37_RS07125 (E1H37_07240) | rnpM | 1451887..1452168 (+) | 282 | WP_003419469.1 | RNase P modulator RnpM | - |
| E1H37_RS07130 (E1H37_07245) | - | 1452158..1452469 (+) | 312 | WP_003419470.1 | L7Ae/L30e/S12e/Gadd45 family ribosomal protein | - |
| E1H37_RS07135 (E1H37_07250) | infB | 1452491..1454431 (+) | 1941 | WP_003438306.1 | translation initiation factor IF-2 | - |
| E1H37_RS07140 (E1H37_07255) | rbfA | 1454474..1454854 (+) | 381 | WP_003428234.1 | 30S ribosome-binding factor RbfA | - |
| E1H37_RS07145 (E1H37_07260) | - | 1454835..1455512 (+) | 678 | Protein_1320 | DHH family phosphoesterase | - |
| E1H37_RS07150 (E1H37_07270) | tnpB | 1456152..1457270 (+) | 1119 | WP_032548186.1 | IS200/IS605 family element RNA-guided endonuclease TnpB | - |
| E1H37_RS07155 (E1H37_07275) | - | 1457388..1457693 (+) | 306 | Protein_1322 | DHH family phosphoesterase | - |
| E1H37_RS07160 (E1H37_07280) | truB | 1457706..1458611 (+) | 906 | WP_003428232.1 | tRNA pseudouridine(55) synthase TruB | - |
| E1H37_RS07165 (E1H37_07285) | - | 1458742..1459671 (+) | 930 | WP_003438310.1 | bifunctional riboflavin kinase/FAD synthetase | - |
| E1H37_RS07170 (E1H37_07295) | rpsO | 1459775..1460032 (+) | 258 | WP_003419491.1 | 30S ribosomal protein S15 | - |
| E1H37_RS07175 (E1H37_07300) | - | 1460272..1461117 (+) | 846 | WP_009889099.1 | DegV family protein | - |
| E1H37_RS07180 (E1H37_07305) | pnp | 1461242..1463353 (+) | 2112 | WP_003438316.1 | polyribonucleotide nucleotidyltransferase | - |
| E1H37_RS07185 (E1H37_07310) | - | 1463619..1464362 (+) | 744 | WP_003438319.1 | polysaccharide deacetylase family protein | - |
| E1H37_RS07190 (E1H37_07315) | - | 1464520..1465767 (+) | 1248 | WP_009902409.1 | M16 family metallopeptidase | - |
| E1H37_RS07195 (E1H37_07320) | - | 1465802..1466047 (+) | 246 | WP_021364423.1 | YlmC/YmxH family sporulation protein | - |
| E1H37_RS07200 (E1H37_07325) | dapG | 1466057..1467280 (+) | 1224 | WP_003438324.1 | aspartate kinase | - |
| E1H37_RS07205 (E1H37_07330) | - | 1467393..1468127 (+) | 735 | WP_021364422.1 | ClpP family protease | - |
| E1H37_RS07210 (E1H37_07335) | - | 1468250..1470661 (+) | 2412 | WP_003438328.1 | FtsK/SpoIIIE family DNA translocase | - |
| E1H37_RS07215 (E1H37_07340) | mnmH | 1470664..1471722 (+) | 1059 | WP_003433322.1 | tRNA 2-selenouridine(34) synthase MnmH | - |
| E1H37_RS07220 (E1H37_07345) | rimO | 1471716..1473050 (+) | 1335 | WP_003433320.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
| E1H37_RS07225 (E1H37_07350) | pgsA | 1473037..1473579 (+) | 543 | WP_009889106.1 | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase | - |
| E1H37_RS07230 (E1H37_07355) | recA | 1473867..1474913 (+) | 1047 | WP_021364420.1 | recombinase RecA | Machinery gene |
| E1H37_RS07235 (E1H37_07360) | rny | 1475089..1476630 (+) | 1542 | WP_003428216.1 | ribonuclease Y | - |
| E1H37_RS07240 (E1H37_07365) | - | 1477265..1479046 (+) | 1782 | WP_003438344.1 | UvrD-helicase domain-containing protein | - |
| E1H37_RS07245 (E1H37_07370) | lepB | 1479128..1479658 (-) | 531 | WP_009902411.1 | signal peptidase I | - |
| E1H37_RS07250 (E1H37_07375) | - | 1479698..1480522 (-) | 825 | WP_003438350.1 | undecaprenyl-diphosphate phosphatase | - |
| E1H37_RS07255 (E1H37_07380) | - | 1480779..1481687 (+) | 909 | WP_009889110.1 | tyrosine-type recombinase/integrase | - |
| E1H37_RS07260 (E1H37_07385) | purB | 1481831..1483276 (+) | 1446 | WP_003438353.1 | adenylosuccinate lyase | - |
| E1H37_RS07265 (E1H37_07390) | - | 1483587..1484039 (+) | 453 | WP_003419561.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| E1H37_RS07270 (E1H37_07395) | - | 1484451..1486028 (+) | 1578 | WP_021364419.1 | PTS transporter subunit EIIC | - |
| E1H37_RS07275 (E1H37_07400) | - | 1486176..1486928 (+) | 753 | WP_009892977.1 | MurR/RpiR family transcriptional regulator | - |
| E1H37_RS07280 (E1H37_07405) | - | 1487061..1488407 (+) | 1347 | WP_009902417.1 | 6-phospho-alpha-glucosidase | - |
| E1H37_RS07285 (E1H37_07410) | - | 1488519..1489715 (-) | 1197 | WP_003438357.1 | pyridoxal phosphate-dependent aminotransferase | - |
| E1H37_RS07290 (E1H37_07415) | galT | 1490100..1491050 (+) | 951 | WP_009889113.1 | galactose-1-phosphate uridylyltransferase | - |
| E1H37_RS07295 (E1H37_07420) | - | 1491211..1491963 (+) | 753 | WP_003438367.1 | exodeoxyribonuclease III | - |
| E1H37_RS07300 (E1H37_07425) | - | 1492055..1492831 (-) | 777 | WP_009896237.1 | 3'-5' exonuclease | - |
| E1H37_RS07305 (E1H37_07430) | - | 1493146..1495044 (+) | 1899 | WP_003428202.1 | glutamine synthetase | - |
| E1H37_RS07310 (E1H37_07435) | - | 1495172..1496293 (-) | 1122 | WP_003438374.1 | MGDG synthase family glycosyltransferase | - |
| E1H37_RS07315 (E1H37_07440) | - | 1496492..1496824 (+) | 333 | WP_009889116.1 | PadR family transcriptional regulator | - |
| E1H37_RS07320 (E1H37_07445) | - | 1496811..1497869 (+) | 1059 | WP_021367719.1 | DUF1700 domain-containing protein | - |
| E1H37_RS07325 (E1H37_07450) | - | 1497862..1498932 (+) | 1071 | WP_021364425.1 | DUF4097 family beta strand repeat-containing protein | - |
| E1H37_RS07330 (E1H37_07455) | - | 1499034..1499570 (+) | 537 | WP_003428196.1 | lipoprotein | - |
| E1H37_RS07335 (E1H37_07460) | - | 1499686..1500393 (+) | 708 | WP_009902422.1 | lantibiotic protection ABC transporter ATP-binding protein | - |
| E1H37_RS07340 (E1H37_07465) | - | 1500395..1501111 (+) | 717 | WP_009896246.1 | lantibiotic immunity ABC transporter MutE/EpiE family permease subunit | - |
| E1H37_RS07345 (E1H37_07470) | - | 1501113..1501871 (+) | 759 | WP_009902423.1 | lantibiotic immunity ABC transporter MutG family permease subunit | - |
| E1H37_RS07350 (E1H37_07475) | - | 1502006..1503394 (+) | 1389 | WP_021364432.1 | two-component system sensor histidine kinase | - |
| E1H37_RS07355 (E1H37_07480) | - | 1503470..1504291 (-) | 822 | WP_021364435.1 | pyridoxamine kinase | - |
| E1H37_RS07360 (E1H37_07485) | - | 1504542..1505696 (+) | 1155 | WP_009902426.1 | amidase domain-containing protein | - |
| E1H37_RS07365 (E1H37_07490) | - | 1505879..1506079 (+) | 201 | WP_003419624.1 | cold-shock protein | - |
| E1H37_RS07370 (E1H37_07495) | - | 1506500..1506928 (+) | 429 | WP_009889129.1 | CBS domain-containing protein | - |
| E1H37_RS07375 (E1H37_07500) | - | 1507071..1507826 (-) | 756 | WP_009889131.1 | peptidylprolyl isomerase | - |
| E1H37_RS07380 (E1H37_07510) | - | 1508527..1509033 (-) | 507 | WP_003428186.1 | ImmA/IrrE family metallo-endopeptidase | - |
| E1H37_RS07385 (E1H37_07515) | - | 1509115..1509435 (-) | 321 | WP_003428185.1 | XRE family transcriptional regulator | - |
| E1H37_RS07390 (E1H37_07520) | - | 1509604..1509801 (+) | 198 | WP_003419641.1 | helix-turn-helix transcriptional regulator | - |
| E1H37_RS07395 (E1H37_07525) | - | 1509906..1510346 (+) | 441 | WP_003428183.1 | hypothetical protein | - |
| E1H37_RS07400 (E1H37_07530) | - | 1510595..1511038 (+) | 444 | WP_003438413.1 | phage tail terminator family protein | - |
| E1H37_RS07405 (E1H37_07535) | - | 1511043..1512107 (+) | 1065 | WP_003438414.1 | phage tail sheath subtilisin-like domain-containing protein | - |
| E1H37_RS07410 (E1H37_07540) | - | 1512121..1512549 (+) | 429 | WP_003419646.1 | phage tail tube protein | - |
Sequence
Protein
Download Length: 348 a.a. Molecular weight: 37389.74 Da Isoelectric Point: 4.8236
>NTDB_id=350045 E1H37_RS07230 WP_021364420.1 1473867..1474913(+) (recA) [Clostridioides difficile strain Cd14]
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTGAIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSC
VASAQKDGGIAAFIDAEHALDPVYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKFYSSVRLDVRKIDTIKQGDKVIG
SRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLLDIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEI
DEKVRAFYNLNEEHEESGISVSKEIVEE
Nucleotide
Download Length: 1047 bp
>NTDB_id=350045 E1H37_RS07230 WP_021364420.1 1473867..1474913(+) (recA) [Clostridioides difficile strain Cd14]
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
ATGAGTGTAGATCAAGAAAAATTAAAAGCGTTGAATGAAGCTTTAGGTAAAATTGAAAAAGATTTTGGTAAAGGTTCAGT
AATGAAATTGGGAGAAGCAACATCTATGTCTATAGATGTTATATCAACAGGAGCGATTGGTTTAGACATAGCTATTGGTA
TAGGAGGTCTACCTAGAGGGAGAATAGTTGAAGTATATGGTCCAGAATCTTCTGGTAAAACTACTGTTGCGCTTAGTTGT
GTAGCATCAGCTCAAAAAGATGGAGGAATAGCTGCATTTATAGATGCAGAACATGCACTTGACCCAGTATATGCAAAAGC
TTTGGGTGTGGATGTTGATAACCTAATAATATCTCAACCAGATACAGGTGAACAGGCTTTAGAGATAGCAGAGGCATTGA
TAAGAAGTGGAGCGATAGATATAATAGTAATAGACTCAGTAGCAGCATTAGTTCCAAAGGCTGAAATAGATGGAGATATG
GGTGATTCTCATGTAGGTTTACAAGCTAGACTTATGTCACAAGCACTTAGAAAGTTAACTGGTTCAATTAAAAAATCAAA
TTGTGTTGCTATATTTATAAACCAGTTAAGAGAGAAAGTAGGAATAATGTTTGGAAACCCGGAAACTACTACTGGAGGAC
GTGCACTAAAATTCTATTCATCAGTTAGATTGGATGTTAGAAAAATAGATACAATAAAACAAGGTGATAAAGTTATAGGT
AGTAGAACTAGAGTTAAAGTTGTTAAAAACAAAGTAGCACCACCATTTAAGCAAGCTGAATTTGATATAATGTATGGAGA
AGGAATTTCAAAAATTGGAGACCTTTTAGATATAGCTGCTGATGTAGATATAGTTAAAAAATCAGGTTCATGGTATAGTT
ACAATGATACTAAACTTGGACAAGGAAGAGAAAATGTTAAAAAATTCTTGGAAGATAATTTAGATTTAACTACTGAAATA
GATGAGAAAGTTAGAGCATTTTACAATTTAAATGAAGAACATGAAGAATCAGGTATTTCAGTATCAAAAGAAATTGTAGA
AGAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.