Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | ECSP_RS22115 | Genome accession | NC_013008 |
| Coordinates | 4226569..4227693 (-) | Length | 374 a.a. |
| NCBI ID | WP_000228545.1 | Uniprot ID | A0AAV3H2U0 |
| Organism | Escherichia coli O157:H7 str. TW14359 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Genomic Context
Location: 4221569..4232693
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECSP_RS22085 | yrdA | 4223369..4223923 (+) | 555 | WP_001286216.1 | gamma carbonic anhydrase family protein | - |
| ECSP_RS22090 (ECSP_4251) | yrdB | 4223899..4224156 (-) | 258 | WP_001070590.1 | DUF1488 domain-containing protein | - |
| ECSP_RS22095 (ECSP_4252) | aroE | 4224153..4224971 (-) | 819 | WP_000451254.1 | shikimate dehydrogenase | - |
| ECSP_RS22100 (ECSP_4253) | tsaC | 4224976..4225548 (-) | 573 | WP_001301437.1 | L-threonylcarbamoyladenylate synthase type 1 TsaC | - |
| ECSP_RS22105 (ECSP_4254) | yrdD | 4225553..4226095 (-) | 543 | WP_001129722.1 | type I DNA topoisomerase | - |
| ECSP_RS22110 (ECSP_4255) | smg | 4226124..4226597 (-) | 474 | WP_000460672.1 | DUF494 family protein Smg | - |
| ECSP_RS22115 (ECSP_4256) | dprA | 4226569..4227693 (-) | 1125 | WP_000228545.1 | DNA-protecting protein DprA | Machinery gene |
| ECSP_RS22120 (ECSP_4257) | def | 4227823..4228332 (+) | 510 | WP_000114984.1 | peptide deformylase | - |
| ECSP_RS22125 (ECSP_4258) | fmt | 4228347..4229294 (+) | 948 | WP_000004459.1 | methionyl-tRNA formyltransferase | - |
| ECSP_RS22130 (ECSP_4259) | rsmB | 4229340..4230629 (+) | 1290 | WP_001301795.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| ECSP_RS22135 (ECSP_4260) | trkA | 4230651..4232027 (+) | 1377 | WP_000691382.1 | Trk system potassium transporter TrkA | - |
| ECSP_RS22140 (ECSP_4261) | mscL | 4232157..4232567 (+) | 411 | WP_000022442.1 | large-conductance mechanosensitive channel protein MscL | - |
Sequence
Protein
Download Length: 374 a.a. Molecular weight: 41034.02 Da Isoelectric Point: 6.3845
>NTDB_id=34936 ECSP_RS22115 WP_000228545.1 4226569..4227693(-) (dprA) [Escherichia coli O157:H7 str. TW14359]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGRPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGRPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
Nucleotide
Download Length: 1125 bp
>NTDB_id=34936 ECSP_RS22115 WP_000228545.1 4226569..4227693(-) (dprA) [Escherichia coli O157:H7 str. TW14359]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCGACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCGACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Vibrio campbellii strain DS40M4 |
48.78 |
98.663 |
0.481 |
| dprA | Glaesserella parasuis strain SC1401 |
45.401 |
90.107 |
0.409 |
| dprA | Vibrio cholerae strain A1552 |
49.355 |
82.888 |
0.409 |
| dprA | Haemophilus influenzae Rd KW20 |
44.214 |
90.107 |
0.398 |
| dprA | Legionella pneumophila strain ERS1305867 |
44.545 |
88.235 |
0.393 |