Detailed information    

insolico Bioinformatically predicted

Overview

Name   tfoX   Type   Regulator
Locus tag   EZZ25_RS12545 Genome accession   NZ_CP036499
Coordinates   2664769..2665356 (-) Length   195 a.a.
NCBI ID   WP_001005366.1    Uniprot ID   A0A0K9UTP3
Organism   Vibrio cholerae strain 20000     
Function   master regulator of natural competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 2659769..2670356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZZ25_RS12525 (EZZ25_12525) - 2659997..2661262 (-) 1266 WP_025998897.1 YdgA family protein -
  EZZ25_RS12530 (EZZ25_12530) - 2661485..2663440 (+) 1956 WP_001082988.1 ATP-binding protein -
  EZZ25_RS12535 (EZZ25_12535) - 2663437..2663934 (+) 498 WP_001031967.1 response regulator -
  EZZ25_RS12540 (EZZ25_12540) - 2664125..2664673 (+) 549 WP_001232641.1 hypothetical protein -
  EZZ25_RS12545 (EZZ25_12545) tfoX 2664769..2665356 (-) 588 WP_001005366.1 TfoX/Sxy family DNA transformation protein Regulator
  EZZ25_RS12550 (EZZ25_12550) - 2665734..2666654 (+) 921 WP_000019000.1 HDOD domain-containing protein -
  EZZ25_RS12555 (EZZ25_12555) - 2666675..2667580 (+) 906 WP_000948497.1 lysine exporter LysO family protein -
  EZZ25_RS12560 (EZZ25_12560) - 2667769..2668278 (+) 510 WP_000826868.1 hypothetical protein -
  EZZ25_RS12565 (EZZ25_12565) panP 2668388..2670034 (+) 1647 WP_000253198.1 pyridoxal-dependent aspartate 1-decarboxylase PanP -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22816.03 Da        Isoelectric Point: 6.9718

>NTDB_id=349242 EZZ25_RS12545 WP_001005366.1 2664769..2665356(-) (tfoX) [Vibrio cholerae strain 20000]
MNEQQFFDYVTKFGAYQKRSMFGGIGLFQHDAMYVLVSEDRIFVRGGEELDPELLALGCEKYRHVKKQTTATVNYYDITE
LYEQHHPELDSIIERSIQFSVNQREFQRSAASRRLRDLPNMQLTLERMVKKAGIDDVETFMSLGAPEVFNKVRQAYGSDV
DVKLLWKFAGAIEGIHWKLLQEPRKRQLLESCQQR

Nucleotide


Download         Length: 588 bp        

>NTDB_id=349242 EZZ25_RS12545 WP_001005366.1 2664769..2665356(-) (tfoX) [Vibrio cholerae strain 20000]
ATGAATGAGCAACAGTTTTTCGACTACGTAACTAAGTTTGGCGCCTACCAAAAACGCTCGATGTTTGGTGGTATTGGCTT
GTTTCAACACGACGCTATGTATGTGTTGGTCAGTGAAGACCGCATTTTTGTGCGTGGTGGAGAAGAGCTCGACCCTGAGC
TCTTGGCCTTAGGGTGCGAGAAATATCGCCATGTTAAAAAACAGACAACGGCAACCGTAAACTATTACGACATCACTGAA
CTGTATGAGCAACATCACCCTGAGCTAGACTCGATCATTGAACGCTCGATTCAGTTTTCTGTGAATCAGCGGGAATTTCA
ACGCTCAGCAGCCAGTCGTCGTCTACGGGATTTACCCAATATGCAACTGACTTTGGAGCGTATGGTAAAAAAAGCGGGCA
TTGACGATGTGGAAACTTTTATGAGCCTCGGTGCGCCAGAAGTGTTTAATAAGGTGCGTCAAGCTTATGGAAGTGATGTC
GATGTAAAACTACTGTGGAAGTTTGCGGGTGCGATTGAAGGTATTCACTGGAAACTGCTGCAAGAGCCGCGTAAGCGCCA
ACTGTTAGAAAGTTGTCAGCAGCGTTAA

Domains

Predicted by InterproScan.

TfoX C-terminal domain (TfoX_C)

(112-190)

TfoX N-terminal domain (TfoX_N)

(9-99)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K9UTP3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  tfoX Vibrio cholerae O1 biovar El Tor str. N16961

100

100

1
  tfoX Vibrio cholerae O1 biovar El Tor strain DRC-193A

100

100

1
  tfoX Vibrio cholerae O1 biovar El Tor strain P27459

100

100

1
  tfoX Vibrio cholerae O1 biovar El Tor strain E7946

100

100

1
  tfoX Vibrio cholerae strain A1552

100

100

1
  tfoX Vibrio campbellii strain DS40M4

69.43

98.974

0.687
  tfoX Vibrio parahaemolyticus RIMD 2210633

68.394

98.974

0.677
  tfoX Aliivibrio fischeri ES114

59.043

96.41

0.569

Multiple sequence alignment