Detailed information NTG0349060

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: GJD98_RS06395
• Genome accession: NZ_CP045974
• Coordinates: 1394235..1394912 (-)
• Length: 225 a.a.
• NCBI ID: WP_011213604.1
• Uniprot ID: -
• Organism: Legionella pneumophila strain AUSMDU00010536 isolate SBT211
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1389235..1399912

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJD98_RS06370 (GJD98_06370)	ruvC	1389430..1389954 (+)	525	WP_010947018.1	crossover junction endodeoxyribonuclease RuvC	-
GJD98_RS06375 (GJD98_06375)	ruvA	1389951..1390550 (+)	600	WP_010947019.1	Holliday junction branch migration protein RuvA	-
GJD98_RS06380 (GJD98_06380)	-	1390600..1390920 (+)	321	WP_010947020.1	hypothetical protein	-
GJD98_RS06385 (GJD98_06385)	lem8	1390953..1392539 (-)	1587	WP_010947021.1	Dot/Icm T4SS effector Lem8	-
GJD98_RS06390 (GJD98_06390)	-	1392823..1394238 (-)	1416	WP_010947022.1	ATP-binding protein	-
GJD98_RS06395 (GJD98_06395)	ciaR	1394235..1394912 (-)	678	WP_011213604.1	response regulator	Regulator
GJD98_RS06400 (GJD98_06400)	-	1394973..1395518 (-)	546	WP_010947024.1	septation protein A	-
GJD98_RS06405 (GJD98_06405)	-	1395761..1397200 (-)	1440	WP_010947025.1	LysM peptidoglycan-binding domain-containing protein	-
GJD98_RS06410 (GJD98_06410)	gloB	1397315..1398079 (-)	765	WP_010947026.1	hydroxyacylglutathione hydrolase	-
GJD98_RS06415 (GJD98_06415)	-	1398083..1398931 (-)	849	WP_015444565.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
GJD98_RS06420 (GJD98_06420)	-	1399207..1399416 (+)	210	WP_011213609.1	hypothetical protein	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25151.74 Da
• Isoelectric Point: 4.9981

>NTDB_id=349060 GJD98_RS06395 WP_011213604.1 1394235..1394912(-) (ciaR) [Legionella pneumophila strain AUSMDU00010536 isolate SBT211]
MRLLLVEDDELLGDAVKAGLTQFGYVVDWLKDGEAARAALKSESFELIILDLGLPKLSGLSLLQNIRHDGNSTPVIILTA
RESIEDRVKGLDSGADDYLIKPFDLNELSARIRALVRRSQGRADSVLQYKNITLDPAAHSVFVDDVLVNVPRREFALLQK
LLENSGQVLSREQLMQSIYGWEEDVDSNALEVHIHNLRKKLNANFIRTIRGVGYMAEKNDSVLLS

Nucleotide

• Length: 678 bp

>NTDB_id=349060 GJD98_RS06395 WP_011213604.1 1394235..1394912(-) (ciaR) [Legionella pneumophila strain AUSMDU00010536 isolate SBT211]
ATGAGATTATTACTTGTTGAAGACGATGAACTGCTTGGCGATGCAGTAAAAGCCGGACTGACACAATTTGGTTATGTTGT
TGACTGGCTAAAAGATGGCGAAGCTGCTCGGGCGGCTCTCAAATCAGAGTCTTTTGAATTAATTATTCTTGACTTGGGAT
TACCTAAATTATCCGGTTTATCATTATTGCAAAACATCAGACATGATGGAAATAGCACACCTGTGATTATTCTTACAGCT
CGAGAATCAATAGAAGATCGGGTAAAAGGCTTAGATAGCGGTGCTGACGATTATCTTATTAAGCCTTTTGATTTAAACGA
ATTAAGTGCAAGGATTAGAGCATTGGTAAGGCGCTCTCAGGGCAGAGCTGATTCCGTGTTGCAATATAAAAATATTACTC
TCGATCCTGCTGCTCATTCTGTCTTCGTGGATGATGTACTCGTCAATGTTCCAAGAAGAGAATTTGCTCTATTGCAGAAA
TTACTTGAAAACAGTGGCCAGGTTTTATCTCGAGAACAATTAATGCAGAGTATTTATGGCTGGGAAGAAGACGTGGACAG
TAATGCTCTCGAAGTTCATATACATAATTTACGTAAAAAACTTAACGCAAACTTTATCCGCACTATACGTGGTGTAGGAT
ATATGGCTGAAAAAAATGACAGTGTACTTCTATCGTGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (148-215)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae D39	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae R6	38.356	97.333	0.373
ciaR	Streptococcus pneumoniae TIGR4	38.356	97.333	0.373
ciaR	Streptococcus mutans UA159	37.9	97.333	0.369
micA	Streptococcus pneumoniae Cp1015	35.345	100	0.364