Detailed information NTG0348864

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GJE16_RS09285
• Genome accession: NZ_CP045931
• Coordinates: 1823939..1824760 (-)
• Length: 273 a.a.
• NCBI ID: WP_000904827.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain AUSMDU00010538
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1818939..1829760

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJE16_RS09260 (GJE16_09260)	rsmA	1819164..1820036 (-)	873	WP_001216852.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
GJE16_RS09265 (GJE16_09265)	-	1820287..1820580 (-)	294	WP_000333255.1	hypothetical protein	-
GJE16_RS09270 (GJE16_09270)	-	1820573..1821214 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
GJE16_RS09275 (GJE16_09275)	-	1821216..1823246 (-)	2031	WP_000825244.1	bacteriocin-associated integral membrane family protein	-
GJE16_RS09280 (GJE16_09280)	-	1823323..1823619 (-)	297	WP_000815392.1	lactococcin 972 family bacteriocin	-
GJE16_RS09285 (GJE16_09285)	comR	1823939..1824760 (-)	822	WP_000904827.1	helix-turn-helix domain-containing protein	Regulator
GJE16_RS09290 (GJE16_09290)	rnmV	1824832..1825392 (-)	561	WP_000660019.1	ribonuclease M5	-
GJE16_RS09295 (GJE16_09295)	-	1825392..1826165 (-)	774	WP_000575601.1	TatD family hydrolase	-
GJE16_RS09300 (GJE16_09300)	-	1826470..1827441 (-)	972	Protein_1812	DUF1542 domain-containing protein	-
GJE16_RS09305 (GJE16_09305)	rpmH	1827647..1827781 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
GJE16_RS09310 (GJE16_09310)	-	1828189..1829142 (+)	954	WP_001155339.1	IS30-like element ISSpn8 family transposase	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 32180.61 Da
• Isoelectric Point: 6.1110

>NTDB_id=348864 GJE16_RS09285 WP_000904827.1 1823939..1824760(-) (comR) [Streptococcus pneumoniae strain AUSMDU00010538]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLLIRLFFYQMLIRKDLAKFINQIEKLML
FLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAES
FYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 822 bp

>NTDB_id=348864 GJE16_RS09285 WP_000904827.1 1823939..1824760(-) (comR) [Streptococcus pneumoniae strain AUSMDU00010538]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTATGATAAGAAAGAAGCGTGTTTGGATACTTCTAGAACTAGAAGGCC
TGAATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGT
TGATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTC
TTTCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTG
TCTTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATT
ATCAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCA
TTTTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGA
GGATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (94-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	34.564	100	0.377
comR	Streptococcus mutans UA159	34.354	100	0.37
comR	Streptococcus suis P1/7	34.364	100	0.366
comR	Streptococcus suis 05ZYH33	34.364	100	0.366
comR	Streptococcus pyogenes MGAS315	33.333	100	0.366